wingless-type MMTV integration site family, member 7A

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Synonym

WNT7A, Protein Wnt-7a precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:18.90 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.44 cerebellum:5.34 brain stem:5.40 corpus callosum/glia:5.24 pineal gland:- peripheral nerve:5.19 spine:5.35 retina:- eye:- artery/aorta:5.34 vein:5.60 lymphnode:5.33 peripheral blood:- spleen:5.24 thymus:5.52 bone marrow:5.34 adipose:5.31 bone:- skin:5.34
CAGE cerebrum:1.58 cerebellum:- brain stem:1.44 corpus callosum/glia:1.38 pineal gland:0.21 peripheral nerve:- spine:1.58 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0.86 peripheral blood:- spleen:1.18 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:1.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.02 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.03 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:18.20 prostate:- ovary:- testis:17.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.30 placenta:5.46 prostate:5.06 ovary:5.04 testis:5.55 heart:5.39 muscle:5.58 esophagus:5.40 stomach:5.15 intestine:5.37 colon:5.46 liver/hepato:5.30 lung:5.42 bladder:- kidney:5.31 pituitary:5.29 thyroid/parathyroid:5.15 adrenal gland:5.25 pancreas:5.48 breast:5.12 salivary:5.28
CAGE uterus:0.41 placenta:3.08 prostate:0.39 ovary:0.20 testis:0.40 heart:0.13 muscle:0 esophagus:0.26 stomach:- intestine:0 colon:0.04     liver/hepato:0    lung:1.60 bladder:0.18 kidney:0.21 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.27 ovary:0.13 testis:0.84 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0.51    bladder:- kidney:0.20 pituitary:- thyroid/parathyroid:0.02 adrenal gland:0.10 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_004625
Gene ID 7476
Unigene ID Hs.72290
Probe set ID 210248_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000154764
GTEx ID ENSG00000154764

Orthologous Gene

Mouse[1]  NM_009527
Rat [0]  

Chromosomal Region

3p25.1  [13,857,755  -  13,921,618]

Gene Family (Interpro ID)

IPR005816  Secreted growth factor Wnt protein
IPR005817  Wnt superfamily
IPR013300  Wnt-7 protein

Link to Pubmed  (Pubmed ID)

8167409
8168088
8893824
9161407
9790192
11070089
11232041
11784006
12477932
12843296
12857724
12893825
12937339
14550385
15040835
15082716
15705594
15802269
16169070
16258938
16826533
16835228
17201809
17202865
17588571
18230341
18413325
18538017
18606951
18986540
19054571
19159115
19171330
19453261
19849868
20083228
20219685
20379614
20470940
20501643
20503388
20709709
20845993
20949531
21271649
21344627
22177312
22232518
22294752
22403725
22987443
23056560
23144326
23321718
23727605
24711502

Gene Ontology  (GO ID)

Biological Process

GO:0008105  asymmetric protein localization
GO:0001502  cartilage condensation
GO:0045165  cell fate commitment
GO:0021846  cell proliferation in forebrain
GO:0022009  central nervous system vasculogenesis
GO:0021707  cerebellar granule cell differentiation
GO:0002062  chondrocyte differentiation
GO:0009953  dorsal/ventral pattern formation
GO:0000578  embryonic axis specification
GO:0042733  embryonic digit morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0035116  embryonic hindlimb morphogenesis
GO:0030010  establishment of cell polarity
GO:0060066  fallopian tube development
GO:0070307  lens fiber cell development
GO:0043066  negative regulation of apoptosis
GO:0050768  negative regulation of neurogenesis
GO:0030182  neuron differentiation
GO:0007269  neurotransmitter secretion
GO:0060021  palate development
GO:0060054  positive regulation of epithelial cell proliferation involved in wound healing
GO:0046330  positive regulation of JNK cascade
GO:0051965  positive regulation of synaptogenesis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0031133  regulation of axon diameter
GO:0043627  response to estrogen stimulus
GO:0014719  satellite cell activation
GO:0014834  satellite cell maintenance involved in skeletal muscle regeneration
GO:0007548  sex differentiation
GO:0048103  somatic stem cell division
GO:0048864  stem cell development
GO:0050808  synapse organization
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0009986  cell surface
GO:0005788  endoplasmic reticulum lumen
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005796  Golgi lumen
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005125  cytokine activity
GO:0005109  frizzled binding
GO:0048018  receptor agonist activity
GO:0005102  receptor binding