Wilms tumor 1

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Synonym

Wilms' tumor protein, Wilms tumor 1, GUD, WT33, WT1, WAGR, WIT-2

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:18.90 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.06 cerebellum:3.82 brain stem:4.12 corpus callosum/glia:3.91 pineal gland:- peripheral nerve:4.08 spine:4.04 retina:- eye:- artery/aorta:4.22 vein:4.23 lymphnode:3.95 peripheral blood:- spleen:4.77 thymus:3.68 bone marrow:4.16 adipose:4.37 bone:- skin:4.28
CAGE cerebrum:0.08 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:1.03 vein:1.03 lymphnode:0.20 peripheral blood:- spleen:3.22 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:109.40 placenta:3.60 prostate:11.30 ovary:37.30 testis:155.80 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:6.03 placenta:3.85 prostate:3.74 ovary:6.61 testis:5.50 heart:4.48 muscle:4.30 esophagus:3.89 stomach:3.86 intestine:4.19 colon:4.01 liver/hepato:3.99 lung:3.89 bladder:- kidney:4.46 pituitary:4.10 thyroid/parathyroid:3.78 adrenal gland:3.79 pancreas:4.37 breast:3.92 salivary:4
CAGE uterus:4.28 placenta:2.51 prostate:0.85 ovary:4.52 testis:4.05 heart:1.23 muscle:0 esophagus:0.40 stomach:- intestine:0.27 colon:0.54     liver/hepato:0    lung:0.50 bladder:1.06 kidney:2.24 pituitary:0 thyroid/parathyroid:0.12 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.12 ovary:1.67 testis:0.00 heart:0.19 muscle:0.00 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0.07    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0 adrenal gland:0.02 pancreas:- breast:0.00 salivary:-

IDs

Refseq ID NM_000378
Gene ID 7490
Unigene ID Hs.591980
Probe set ID 216953_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000184937
GTEx ID ENSG00000184937

Orthologous Gene

Mouse[1]  NM_144783
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1302008
1313285
1317572
1332065
1338906
1572653
1654525
1655284
1658787
1662794
1671709
2154335
2154702
2173145
6088386
7585606
7588596
7720589
7731725
7856737
7862533
7862627
7926762
8012395
8086342
8098976
8112732
8119964
8290269
8295405
8306891
8388765
8389468
8393820
8401592
8414514
8621495
8798754
8943350
8956030
9006935
9108089
9178767
9361029
9366517
9475094
9529364
9553041
9556563
9765217
9784496
9815658
10101119
10490105
10571943
10744705
10838070
11001926
11182928
11237525
11278547
11595161
11738793
11889045
11912180
11919196
11933209
11939727
11960373
11986946
12070003
12111123
12127961
12133898
12151099
12161615
12199781
12200377
12213901
12239212
12411326
12444079
12471221
12477932
12665546
12681485
12761165
12802290
12824878
12824921
12829997
12841384
12841869
12901797
12914969
12960088
12961083
12970737
14603255
14666652
14681303
14701728
14702039
14736876
14767530
14962262
14988020
14988155
15084838
15150775
15223639
15253707
15266301
15286719
15297187
15339675
15365188
15483024
15489334
15504250
15504938
15506928
15510596
15518539
15520190
15534117
15538407
15540161
15661271
15674342
15687485
15696971
15780077
15838390
15845894
15878620
15894924
15927676
15957141
15961562
15982325
16087727
16260903
16467207
16502587
16518414
16554811
16780544
16828156
16857797
16876863
16883592
16909243
16920711
16924231
16927106
16934801
16966277
16987884
16990584
17160023
17205055
17206472
17210670
17216259
17371932
17487399
17496156
17508006
17524167
17531467
17540436
17541636
17551084
17579045
17599043
17605875
17630404
17665418
17688410
17706117
17716689
17721194
17728783
17803653
17848411
17853480
17869219
17886559
17912546
17934764
17939399
17940140
17947653
17956689
17972942
18034345
18042071
18058136
18064385
18064689
18065803
18081724
18094593
18181329
18202757
18212735
18231640
18231915
18255279
18260155
18271004
18273617
18292948
18311776
18371184
18385267
18424770
18425046
18443273
18464243
18466223
18469795
18516627
18528287
18559874
18590714
18591546
18604725
18618575
18644985
18666806
18688870
18703217
18708366
18722603
18751389
18752126
18756326
18801058
18929401
18950857
18972317
19017365
19050011
19067769
19097357
19099861
19120973
19137020
19141860
19169475
19171881
19190340
19205749
19212333
19221039
19236519
19250757
19321755
19322206
19351817
19404640
19407365
19416806
19437143
19443388
19447967
19494353
19536888
19549856
19578047
19605546
19615003
19618455
19638168
19730683
19747485
19749460
19752335
19776535
19811333
19817904
19847202
19856421
19951528
20013787
20016532
20025481
20038731
20092642
20122399
20150449
20174665
20204298
20301471
20301533
20301534
20332316
20368469
20368538
20376582
20379614
20412098
20413658
20435628
20442368
20442690
20450766
20507940
20561402
20591825
20592250
20595692
20619105
20619457
20644087
20651072
20678218
20736771
20842112
20849384
20861915
20871039
20880116
20885852
20959405
20971509
20972333
20974136
21057459
21097671
21135860
21189373
21189390
21209057
21256590
21269271
21269566
21344764
21378168
21390327
21447831
21499692
21504297
21508141
21607557
21643023
21658388
21659357
21673345
21697701
21710692
21734473
21760594
21798259
21804407
21851196
21867623
21888469
21896989
21898091
21900206
21909685
21942328
21967832
21980157
21985433
21988832
22015946
22030397
22040952
22093791
22148937
22152856
22172722
22238403
22242671
22246978
22261458
22276610
22306650
22313360
22382985
22391154
22415091
22434317
22506617
22510877
22555024
22558480
22585769
22623625
22672247
22688351
22796116
22797561
22800892
22875062
22876585
22895555
22898820
22915059
22925896
22939983
23042785
23070125
23110324
23110703
23111196
23142971
23207289
23298185
23338265
23362234
23394625
23403166
23460320
23480492
23484026
23544132
23550799
23554000
23584566
23672350
23699597
23706170
23715653
23788249
23832418
23871158
23874238
23898100
23936312
23945386
23956224
23979985
24057671
24161391
24211094
24257751
24265486
24321497
24338413
24503796
24596380
24633336
24778040

Gene Ontology  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0043010  camera-type eye development
GO:0060923  cardiac muscle cell fate commitment
GO:0071320  cellular response to cAMP
GO:0071371  cellular response to gonadotropin stimulus
GO:0060539  diaphragm development
GO:0006309  DNA fragmentation involved in apoptosis
GO:0030855  epithelial cell differentiation
GO:0007281  germ cell development
GO:0032836  glomerular basement membrane development
GO:0032835  glomerulus development
GO:0008406  gonad development
GO:0007507  heart development
GO:0001822  kidney development
GO:0030539  male genitalia development
GO:0008584  male gonad development
GO:0060231  mesenchymal to epithelial transition
GO:0043066  negative regulation of apoptosis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0017148  negative regulation of translation
GO:0060421  positive regulation of heart growth
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0003156  regulation of organ formation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0008380  RNA splicing
GO:0007530  sex determination
GO:0007356  thorax and anterior abdomen determination
GO:0009888  tissue development
GO:0001657  ureteric bud development
GO:0001570  vasculogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0016607  nuclear speck
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0070742  C2H2 zinc finger domain binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0003723  RNA binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding