MYST histone acetyltransferase (monocytic leukemia) 3

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Synonym

RUNXBP2, ZNF220, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3, MYST protein 3, Zinc finger protein 220, Monocytic leukemia zinc finger protein, MYST3, MOZ, Histone acetyltransferase MYST3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:19.20
GeneChip cerebrum:7.78 cerebellum:8.19 brain stem:7.59 corpus callosum/glia:8.27 pineal gland:- peripheral nerve:8.13 spine:7.91 retina:- eye:- artery/aorta:8.11 vein:7.88 lymphnode:8.48 peripheral blood:- spleen:8.56 thymus:8.75 bone marrow:7.99 adipose:8.18 bone:- skin:8.47
CAGE cerebrum:3.93 cerebellum:- brain stem:4.09 corpus callosum/glia:4.15 pineal gland:4.22 peripheral nerve:- spine:4.42 retina:- eye:- artery/aorta:4.19 vein:4.30 lymphnode:4.24 peripheral blood:- spleen:4.17 thymus:4.37 bone marrow:- adipose:4.24 bone:- skin:-
RNA-seq cerebrum:1.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.06 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.53 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:- prostate:45.10 ovary:- testis:- heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:31.20 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip uterus:8.35 placenta:8.40 prostate:8.30 ovary:8.29 testis:8.04 heart:7.73 muscle:7.83 esophagus:7.97 stomach:8.09 intestine:7.43 colon:7.53 liver/hepato:7.68 lung:8.60 bladder:- kidney:7.67 pituitary:8.05 thyroid/parathyroid:8.19 adrenal gland:7.79 pancreas:6.95 breast:8.54 salivary:7.61
CAGE uterus:4.20 placenta:4.14 prostate:3.80 ovary:4.02 testis:3.89 heart:3.85 muscle:3.60 esophagus:3.60 stomach:- intestine:3.92 colon:3.88     liver/hepato:3.08    lung:4.31 bladder:4.02 kidney:3.51 pituitary:4.19 thyroid/parathyroid:3.58 adrenal gland:- pancreas:3.69 breast:4.31 salivary:3.44
RNA-seq uterus:- placenta:- prostate:0.91 ovary:1.43 testis:1.46 heart:1.40 muscle:0.44 esophagus:- stomach:- intestine:- colon:0.37     liver/hepato:0.12        lung:1.79    bladder:- kidney:1.18 pituitary:- thyroid/parathyroid:0.55 adrenal gland:0.84 pancreas:- breast:0.07 salivary:-

Gene Information

IDs

Refseq ID NM_001099412
Gene ID 7994
Unigene ID Hs.491577
Probe set ID 202423_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000083168
GTEx ID ENSG00000083168

Orthologous Gene

Mouse[1]  NM_001081149
Rat[1]  NM_001100570

Chromosomal Region

8p11.21  [41,786,997  -  41,909,508]

Gene Family (Interpro ID)

IPR005818  Histone H1/H5
IPR011991  Winged helix repressor DNA-binding
IPR019787  Zinc finger, PHD-finger
IPR001965  Zinc finger, PHD-type

Link to Pubmed  (Pubmed ID)

8782817
8849440
9558366
10824998
11313971
11742995
11965546
12477932
12676584
12771199
14702039
15331439
15342556
15657427
16096645
16344560
16387653
16613851
16702405
16713569
16916647
17081983
17083329
17182677
17296583
17697320
17805331
17925393
18469222
18528428
18754862
18794358
18818702
18854154
19001415
19322201
19690564
20581860
20800603
21880731
21890473
22713874
23022987
23063713
23347099
23431171
23994619
24150941
24258712
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006323  DNA packaging
GO:0035162  embryonic hemopoiesis
GO:0060325  face morphogenesis
GO:0003007  heart morphogenesis
GO:0016573  histone acetylation
GO:0043966  histone H3 acetylation
GO:0030099  myeloid cell differentiation
GO:0043433  negative regulation of transcription factor activity
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0006334  nucleosome assembly
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006473  protein amino acid acetylation
GO:0035019  somatic stem cell maintenance
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0070776  MOZ/MORF histone acetyltransferase complex
GO:0005730  nucleolus
GO:0000786  nucleosome
GO:0005634  nucleus
GO:0016605  PML body

Molecular Function

GO:0016407  acetyltransferase activity
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0004402  histone acetyltransferase activity
GO:0005515  protein binding
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding
GO:0008270  zinc ion binding