solute carrier family 24 (sodium/potassium/calcium exchanger), member 6

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Synonym

Solute carrier family 24 member 6, NCLX, Sodium/potassium/calcium exchanger 6 precursor, SLC24A6, NCKX6, FLJ22233, Na(+)/K(+)/Ca(2+)-exchange protein 6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:49.80 cerebellum:100.80 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:80.90 peripheral blood:182.20 spleen:37.80 thymus:425.20 bone marrow:78.70 adipose:40.30 bone:102.40 skin:-
GeneChip cerebrum:5.66 cerebellum:5.86 brain stem:5.64 corpus callosum/glia:5.64 pineal gland:- peripheral nerve:5.77 spine:5.70 retina:- eye:- artery/aorta:5.98 vein:5.84 lymphnode:6.06 peripheral blood:- spleen:6.25 thymus:6.35 bone marrow:6.35 adipose:6.03 bone:- skin:6.04
CAGE cerebrum:2.24 cerebellum:- brain stem:2.52 corpus callosum/glia:2.79 pineal gland:1.59 peripheral nerve:- spine:2.96 retina:- eye:- artery/aorta:3.25 vein:3.12 lymphnode:3.52 peripheral blood:- spleen:3.57 thymus:3.74 bone marrow:- adipose:3.10 bone:- skin:-
RNA-seq cerebrum:1.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.07 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.62 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:29.10 prostate:11.30 ovary:74.50 testis:103.80 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:- colon:42.40     liver/hepato:21.10        lung:48.90    bladder:125.60 kidney:52 pituitary:232 thyroid/parathyroid:- adrenal gland:101.60 pancreas:- breast:18.60 salivary:-
GeneChip uterus:5.65 placenta:5.81 prostate:5.66 ovary:6.09 testis:5.88 heart:5.80 muscle:5.85 esophagus:5.93 stomach:5.81 intestine:5.88 colon:5.91 liver/hepato:5.84 lung:6.07 bladder:- kidney:5.94 pituitary:6.18 thyroid/parathyroid:5.72 adrenal gland:7.04 pancreas:6 breast:5.79 salivary:6
CAGE uterus:3.01 placenta:3.20 prostate:2.85 ovary:4.09 testis:3.13 heart:2.93 muscle:2.02 esophagus:2.74 stomach:- intestine:3.18 colon:3.28     liver/hepato:3.31    lung:3.33 bladder:2.55 kidney:2.90 pituitary:1.69 thyroid/parathyroid:2.44 adrenal gland:- pancreas:2.48 breast:3.06 salivary:2.88
RNA-seq uterus:- placenta:- prostate:2.61 ovary:4.50 testis:2.73 heart:1.33 muscle:1.65 esophagus:- stomach:- intestine:- colon:1.81     liver/hepato:2.47        lung:2.79    bladder:- kidney:2.88 pituitary:- thyroid/parathyroid:2.05 adrenal gland:2.80 pancreas:- breast:2.97 salivary:-

Gene Information

IDs

Refseq ID NM_024959
Gene ID 80024
Unigene ID Hs.286194
Probe set ID 218749_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000089060
GTEx ID ENSG00000089060

Orthologous Gene

Mouse[1]  NM_001177594, NM_001177595, NM_133221
Rat[1]  NM_001017488, NM_001177595, NM_133221

Chromosomal Region

12q24.13  [113,736,564  -  113,797,298]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
12477932
14625281
14702039
15060069
15489334
21890473
21906983
23506867
23538132

Gene Ontology  (GO ID)

Biological Process

GO:0042593  glucose homeostasis
GO:0006811  ion transport
GO:0006851  mitochondrial calcium ion transport
GO:0050796  regulation of insulin secretion
GO:0050896  response to stimulus
GO:0055085  transmembrane transport

Cellular Component

GO:0032592  integral to mitochondrial membrane
GO:0005743  mitochondrial inner membrane
GO:0005886  plasma membrane
GO:0042383  sarcolemma

Molecular Function

GO:0005432  calcium:sodium antiporter activity