sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

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Synonym

SEMA6D, Semaphorin-6D precursor, KIAA1479, FLJ11598

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.30 cerebellum:63 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:184 spine:- retina:- eye:29.40 artery/aorta:60 vein:66.60 lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:25.60 skin:19.20
GeneChip cerebrum:5.58 cerebellum:5.05 brain stem:5.59 corpus callosum/glia:5.81 pineal gland:- peripheral nerve:5.54 spine:5.53 retina:- eye:- artery/aorta:5.26 vein:4.79 lymphnode:4.77 peripheral blood:- spleen:4.88 thymus:4.94 bone marrow:4.92 adipose:5.23 bone:- skin:4.62
CAGE cerebrum:3.67 cerebellum:- brain stem:3.49 corpus callosum/glia:3.82 pineal gland:4.91 peripheral nerve:- spine:3.61 retina:- eye:- artery/aorta:3.11 vein:1.53 lymphnode:1.30 peripheral blood:- spleen:0.88 thymus:1.22 bone marrow:- adipose:2.03 bone:- skin:-
RNA-seq cerebrum:0.27 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.02 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:36.40 prostate:- ovary:37.30 testis:4.30 heart:63.90 muscle:20.10 esophagus:- stomach:- intestine:32.40 colon:8.50     liver/hepato:31.70        lung:9.80    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:88.90 breast:- salivary:-
GeneChip uterus:4.86 placenta:5.45 prostate:5.11 ovary:5.46 testis:4.70 heart:5.05 muscle:5.47 esophagus:4.69 stomach:5.44 intestine:5.31 colon:5.35 liver/hepato:5.04 lung:4.92 bladder:- kidney:6.27 pituitary:5.28 thyroid/parathyroid:5.32 adrenal gland:4.67 pancreas:5.03 breast:5.45 salivary:4.61
CAGE uterus:2.28 placenta:3.56 prostate:2.55 ovary:3.09 testis:2.26 heart:2.36 muscle:2.35 esophagus:1.68 stomach:- intestine:4.73 colon:3.50     liver/hepato:1.84    lung:2.50 bladder:1.62 kidney:3.01 pituitary:2.81 thyroid/parathyroid:1.80 adrenal gland:- pancreas:3.40 breast:1.92 salivary:1.15
RNA-seq uterus:- placenta:- prostate:0 ovary:0.23 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.02        lung:0    bladder:- kidney:0.11 pituitary:- thyroid/parathyroid:0.08 adrenal gland:0.16 pancreas:- breast:0.04 salivary:-

Gene Information

IDs

Refseq ID NM_024966
Gene ID 80031
Unigene ID Hs.511265
Probe set ID 220574_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000137872
GTEx ID ENSG00000137872

Orthologous Gene

Mouse[5]  NM_172537, NM_199238, NM_199239, NM_199240, NM_199241
Rat [0]  

Chromosomal Region

15q21.1  [47,704,587  -  48,066,417]

Gene Family (Interpro ID)

IPR003659  Plexin/semaphorin/integrin
IPR001627  Semaphorin/CD100 antigen
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

10819331
11102867
11842242
12110693
12477932
14702039
14977921
16715077
17143962
18029348
19913121
20628086
22911880
23870195

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance

Cellular Component

GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004872  receptor activity
GO:0030215  semaphorin receptor binding