ADAM metallopeptidase domain 12

Synonym

ADAM 12 precursor, ADAM12, MCMP, A disintegrin and metalloproteinase domain 12, MLTNA, ADAM metallopeptidase domain 12 (meltrin alpha), MLTN, Meltrin alpha, MCMPMltna

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.06

cerebellum:4.07

brain stem:4.05

corpus callosum/glia:4.09

pineal gland:-

peripheral nerve:3.96

spine:4.14

retina:-

eye:-

artery/aorta:4.03

vein:3.78

lymphnode:4.26

peripheral blood:-

spleen:4

thymus:4.26

bone marrow:3.93

adipose:4.94

bone:-

skin:4.24

CAGE

cerebrum:0.94

cerebellum:-

brain stem:0.98

corpus callosum/glia:0.79

pineal gland:1.95

peripheral nerve:-

spine:1.34

retina:-

eye:-

artery/aorta:1.22

vein:1.49

lymphnode:1.16

peripheral blood:-

spleen:0.51

thymus:0.74

bone marrow:-

adipose:2.60

bone:-

skin:-

RNA-seq

cerebrum:0.27

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.58

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.24

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:36.40

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.83

placenta:11.70

prostate:3.82

ovary:4.92

testis:3.90

heart:4.05

muscle:3.99

esophagus:3.79

stomach:3.94

intestine:4.45

colon:3.96

liver/hepato:3.94

lung:3.89

bladder:-

kidney:3.93

pituitary:3.93

thyroid/parathyroid:3.83

adrenal gland:3.91

pancreas:4

breast:4.92

salivary:4.22

CAGE

uterus:1.98

placenta:8.13

prostate:1.23

ovary:1.80

testis:1.45

heart:1.00

muscle:0.33

esophagus:0.63

stomach:-

intestine:0.43

colon:0.59

liver/hepato:0

lung:0.97

bladder:2.20

kidney:0.67

pituitary:0.56

thyroid/parathyroid:0.12

adrenal gland:-

pancreas:0.94

breast:2.47

salivary:1.28

RNA-seq

uterus:-

placenta:-

prostate:0.38

ovary:1.10

testis:1.12

heart:0.08

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.26

liver/hepato:0.07

lung:0.43

bladder:-

kidney:0.23

pituitary:-

thyroid/parathyroid:0.19

adrenal gland:1.47

pancreas:-

breast:2.71

salivary:-

IDs

Refseq ID	NM_003474
Gene ID	8038
Unigene ID	Hs.594537
Probe set ID	202952_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000148848
GTEx ID	ENSG00000148848

Orthologous Gene

Mouse[2]	NM_007400
Rat[2]	NM_007400

Chromosomal Region

10q26.2 [127,700,950 - 128,077,024]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000742

EGF-like, type 3

Gene Ontology (GO ID)

Biological Process

GO:0007155	cell adhesion
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0007520	myoblast fusion
GO:0006508	proteolysis

Cellular Component

GO:0005576	extracellular region
GO:0016021	integral to membrane
GO:0005739	mitochondrion
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0004222	metalloendopeptidase activity
GO:0008237	metallopeptidase activity
GO:0005515	protein binding
GO:0017124	SH3 domain binding
GO:0008270	zinc ion binding

ADAM metallopeptidase domain 12

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function