calmodulin 3 (phosphorylase kinase, delta)

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Synonym

CAM2, Calmodulin, CALM3, CALM, CAMB, CALM1, CAMC, CaM, CAM3, calmodulin 3 (phosphorylase kinase, delta), PHKD3, CAM, CAM1, CAMIII, CALM2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:717 cerebellum:642.30 brain stem:- corpus callosum/glia:408.30 pineal gland:148.30 peripheral nerve:521.40 spine:449.20 retina:- eye:246.80 artery/aorta:119.90 vein:- lymphnode:343.80 peripheral blood:200.40 spleen:75.60 thymus:360.70 bone marrow:314.90 adipose:80.70 bone:243.10 skin:110.40
GeneChip cerebrum:9.42 cerebellum:9.42 brain stem:8.84 corpus callosum/glia:7.70 pineal gland:- peripheral nerve:9.32 spine:8.58 retina:- eye:- artery/aorta:8.06 vein:7.67 lymphnode:7.73 peripheral blood:- spleen:7.59 thymus:7.76 bone marrow:7.77 adipose:7.66 bone:- skin:6.93
CAGE cerebrum:4.80 cerebellum:- brain stem:4.10 corpus callosum/glia:3.68 pineal gland:2.89 peripheral nerve:- spine:3.77 retina:- eye:- artery/aorta:4.00 vein:3.67 lymphnode:3.75 peripheral blood:- spleen:3.70 thymus:4.09 bone marrow:- adipose:3.44 bone:- skin:-
RNA-seq cerebrum:8.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.60 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.19 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:182.30 placenta:72.90 prostate:191.50 ovary:633.50 testis:90.90 heart:204.30 muscle:60.30 esophagus:342.80 stomach:254.90 intestine:324 colon:203.50     liver/hepato:10.60        lung:141.70    bladder:502.40 kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:253.90 pancreas:62.20 breast:176.60 salivary:-
GeneChip uterus:7.65 placenta:7.12 prostate:7.25 ovary:7.61 testis:7.74 heart:7.57 muscle:7.18 esophagus:7.07 stomach:7.61 intestine:7.62 colon:8.01 liver/hepato:7.58 lung:7.35 bladder:- kidney:7.66 pituitary:7.60 thyroid/parathyroid:7.93 adrenal gland:7.64 pancreas:6.98 breast:7.70 salivary:6.76
CAGE uterus:3.73 placenta:3.56 prostate:3.86 ovary:4.00 testis:4.26 heart:3.78 muscle:3.97 esophagus:3.50 stomach:- intestine:3.51 colon:3.75     liver/hepato:3.20    lung:3.85 bladder:3.74 kidney:3.24 pituitary:2.79 thyroid/parathyroid:3.56 adrenal gland:- pancreas:3.85 breast:4.15 salivary:3.08
RNA-seq uterus:- placenta:- prostate:7.49 ovary:7.36 testis:7.19 heart:5.80 muscle:5.48 esophagus:- stomach:- intestine:- colon:6.85     liver/hepato:4.81        lung:6.44    bladder:- kidney:6.06 pituitary:- thyroid/parathyroid:6.47 adrenal gland:6.25 pancreas:- breast:5.94 salivary:-

Gene Information

IDs

Refseq ID NM_005184
Gene ID 808
Unigene ID Hs.515487
Probe set ID 200623_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000160014
GTEx ID ENSG00000160014

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

19q13.32  [47,104,566  -  47,114,039]
2p21  [47,272,677  -  47,403,740]
14q32.11  [90,862,846  -  90,874,605]

Gene Family (Interpro ID)

IPR002048  Calcium-binding EF-hand
IPR018249  EF-HAND 2
IPR001125  Recoverin

Link to Pubmed  (Pubmed ID)

1474585
2223880
2244899
2445749
3111527
3182832
6330098
6385987
6457647
7093203
7607248
7803388
7925473
8226798
8312049
8314583
8476923
8573130
8615909
8631777
8702940
8780394
8862395
9096366
9188442
9242710
9256481
9278050
9362478
9580552
9658102
9681195
9804419
9923700
9927666
10373510
10416864
10625668
10692436
10737800
10757985
10781589
10816571
10823944
10880439
10899953
11054265
11072229
11278607
11286509
11448995
11591728
11685248
11710561
11736632
11741295
11807546
11847276
11953448
11981030
11984006
12032157
12051765
12153558
12189141
12221128
12477932
12485993
12508121
12577052
12821674
12871148
14594800
14613930
14622581
14627618
14630798
14701808
14702039
14960328
15032605
15140941
15489334
15592455
15632291
15719022
15723066
15746192
15815621
16127172
16169070
16189514
16229872
16299511
16760425
17046994
17353931
17620599
17719545
18370588
18553937
18567582
18768750
19001277
19322201
19380743
19429631
19913121
20012528
20379146
20628086
20639865
20876399
20956522
21047202
21078624
21145461
21726808
21799007
21906983
21963094
21980498
21987572
22323446
22505724
22939629
23077317
23128233
23798571
24163370
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007202  activation of phospholipase C activity
GO:0007596  blood coagulation
GO:0005975  carbohydrate metabolic process
GO:0005513  detection of calcium ion
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0006006  glucose metabolic process
GO:0005980  glycogen catabolic process
GO:0045087  innate immune response
GO:0043647  inositol phosphate metabolic process
GO:0016044  membrane organization
GO:0006936  muscle contraction
GO:0060315  negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0048011  nerve growth factor receptor signaling pathway
GO:0046209  nitric oxide metabolic process
GO:0007603  phototransduction, visible light
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0030801  positive regulation of cyclic nucleotide metabolic process
GO:0051343  positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0032516  positive regulation of phosphoprotein phosphatase activity
GO:0035307  positive regulation of protein amino acid dephosphorylation
GO:0060316  positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0055117  regulation of cardiac muscle contraction
GO:0010881  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0032465  regulation of cytokinesis
GO:0002027  regulation of heart rate
GO:0050999  regulation of nitric-oxide synthase activity
GO:0010880  regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0022400  regulation of rhodopsin mediated signaling pathway
GO:0001975  response to amphetamine
GO:0051592  response to calcium ion
GO:0051412  response to corticosterone stimulus
GO:0016056  rhodopsin mediated signaling pathway
GO:0007165  signal transduction
GO:0007268  synaptic transmission

Cellular Component

GO:0034704  calcium channel complex
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005654  nucleoplasm
GO:0005886  plasma membrane
GO:0030017  sarcomere
GO:0005876  spindle microtubule
GO:0000922  spindle pole

Molecular Function

GO:0005509  calcium ion binding
GO:0048306  calcium-dependent protein binding
GO:0031997  N-terminal myristoylation domain binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0043274  phospholipase binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0031996  thioesterase binding
GO:0031432  titin binding