capping protein (actin filament) muscle Z-line, beta

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Synonym

MGC129749, CAPPB, F-actin capping protein subunit beta, CAPB, MGC104401, CapZ beta, CAPZB, MGC129750

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:468.10 cerebellum:151.10 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:184 spine:224.60 retina:355.90 eye:176.30 artery/aorta:60 vein:- lymphnode:212.30 peripheral blood:164 spleen:113.40 thymus:141.70 bone marrow:3798.30 adipose:201.70 bone:102.40 skin:1353.60
GeneChip cerebrum:8.90 cerebellum:8.33 brain stem:9.02 corpus callosum/glia:8.77 pineal gland:- peripheral nerve:9.46 spine:9.10 retina:- eye:- artery/aorta:9.58 vein:9.34 lymphnode:9.56 peripheral blood:- spleen:9.83 thymus:9.57 bone marrow:9.49 adipose:9.23 bone:- skin:9.29
CAGE cerebrum:4.33 cerebellum:- brain stem:4.46 corpus callosum/glia:4.63 pineal gland:4.10 peripheral nerve:- spine:4.13 retina:- eye:- artery/aorta:4.87 vein:4.89 lymphnode:4.90 peripheral blood:- spleen:4.86 thymus:4.85 bone marrow:- adipose:4.55 bone:- skin:-
RNA-seq cerebrum:5.43 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.49 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.66 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:164 placenta:859.80 prostate:912.40 ovary:633.50 testis:389.40 heart:127.70 muscle:40.20 esophagus:- stomach:297.40 intestine:226.80 colon:814     liver/hepato:116.10        lung:156.40    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:160 breast:2156 salivary:328.40
GeneChip uterus:9.51 placenta:8.77 prostate:10.04 ovary:9.49 testis:9.24 heart:9 muscle:8.38 esophagus:9.88 stomach:9.47 intestine:9.22 colon:9.45 liver/hepato:8.81 lung:9.21 bladder:- kidney:9.07 pituitary:8.75 thyroid/parathyroid:9.38 adrenal gland:9.22 pancreas:7.98 breast:9.45 salivary:8.60
CAGE uterus:4.81 placenta:4.65 prostate:4.75 ovary:4.75 testis:5.05 heart:4.50 muscle:4.24 esophagus:4.79 stomach:- intestine:4.85 colon:4.60     liver/hepato:4.60    lung:4.39 bladder:4.72 kidney:4.47 pituitary:4.00 thyroid/parathyroid:4.57 adrenal gland:- pancreas:4.28 breast:4.53 salivary:4.40
RNA-seq uterus:- placenta:- prostate:6.45 ovary:6.79 testis:6.86 heart:4.15 muscle:4.32 esophagus:- stomach:- intestine:- colon:6.38     liver/hepato:5.74        lung:6.99    bladder:- kidney:6.13 pituitary:- thyroid/parathyroid:6.39 adrenal gland:7.01 pancreas:- breast:6.03 salivary:-

Gene Information

IDs

Refseq ID NM_004930
Gene ID 832
Unigene ID Hs.432760
Probe set ID 37012_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000077549
GTEx ID ENSG00000077549

Orthologous Gene

Mouse[6]  NM_001037761, NM_009798
Rat[1]  NM_001005903, NM_009798

Chromosomal Region

1p36.13  [19,665,267  -  19,812,066]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7665558
9331217
9354614
12477932
12488317
12665801
14702039
15146197
15489334
16054028
16130169
16169070
16300736
16678097
16710414
17353931
17643375
18457437
19056867
19156129
19615732
19738201
19922875
20379614
20697350
20876399
20884878
21139048
21182205
21319273
21565293
21822214
21844192
21890473
21900206
21906983
22070227
22118674
22234250
22266860
22268729
22482804
22494929
22505724
22623428
22706086
22863883
22939629
22990118
23000965
23084401
23398456
23408906
24163370
24457600
24583282
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0051016  barbed-end actin filament capping
GO:0007596  blood coagulation
GO:0006928  cellular component movement
GO:0007010  cytoskeleton organization
GO:0030032  lamellipodium assembly
GO:0048747  muscle fiber development
GO:0031115  negative regulation of microtubule polymerization
GO:0031175  neuron projection development
GO:0022604  regulation of cell morphogenesis

Cellular Component

GO:0001669  acrosomal vesicle
GO:0015629  actin cytoskeleton
GO:0030863  cortical cytoskeleton
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0008290  F-actin capping protein complex
GO:0014704  intercalated disc
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0071203  WASH complex
GO:0030018  Z disc

Molecular Function

GO:0003779  actin binding
GO:0051015  actin filament binding
GO:0048487  beta-tubulin binding