frizzled homolog 9 (Drosophila)

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Synonym

FzE6, FZD3, hFz9, frizzled (Drosophila) homolog 9, Fz-9, frizzled homolog 9 (Drosophila), Frizzled-9 precursor, FZD9

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.26 cerebellum:5.22 brain stem:5.19 corpus callosum/glia:5.27 pineal gland:- peripheral nerve:4.86 spine:5.12 retina:- eye:- artery/aorta:5.12 vein:5.34 lymphnode:5 peripheral blood:- spleen:4.85 thymus:4.58 bone marrow:5.15 adipose:5.16 bone:- skin:5.23
CAGE cerebrum:1.55 cerebellum:- brain stem:1.77 corpus callosum/glia:1.59 pineal gland:0.71 peripheral nerve:- spine:1.52 retina:- eye:- artery/aorta:1.10 vein:0.59 lymphnode:0.37 peripheral blood:- spleen:0.17 thymus:0.46 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:0.62 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.18 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.38 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.77 placenta:5.02 prostate:4.81 ovary:4.80 testis:5.30 heart:5.22 muscle:5.56 esophagus:5.10 stomach:4.93 intestine:5.27 colon:5.28 liver/hepato:5.04 lung:5.18 bladder:- kidney:4.90 pituitary:5.35 thyroid/parathyroid:4.94 adrenal gland:5 pancreas:5.63 breast:4.87 salivary:5.14
CAGE uterus:0.32 placenta:0.37 prostate:0.88 ovary:0.26 testis:1.84 heart:0.19 muscle:1.20 esophagus:0.40 stomach:- intestine:0.80 colon:0.71     liver/hepato:0    lung:0.10 bladder:0.33 kidney:0.15 pituitary:0.66 thyroid/parathyroid:0.45 adrenal gland:- pancreas:1.42 breast:0 salivary:0.83
RNA-seq uterus:- placenta:- prostate:0.10 ovary:0.08 testis:0.81 heart:0.05 muscle:1.84 esophagus:- stomach:- intestine:- colon:0.22     liver/hepato:0.11        lung:0.04    bladder:- kidney:0.03 pituitary:- thyroid/parathyroid:0.62 adrenal gland:0.14 pancreas:- breast:0.49 salivary:-

Gene Information

IDs

Refseq ID NM_003508
Gene ID 8326
Unigene ID Hs.647029
Probe set ID 207639_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000188763
GTEx ID ENSG00000188763

Orthologous Gene

Mouse[1]  NM_010246
Rat[1]  NM_153305

Chromosomal Region

7q11.23  [72,848,109  -  72,850,450]

Gene Family (Interpro ID)

IPR000539  Frizzled protein
IPR020067  Frizzled-like domain
IPR017981  GPCR, family 2-like

Link to Pubmed  (Pubmed ID)

914765
9147651
9192640
9707618
10198163
12138115
12477932
12853948
14688793
15370539
15705594
16189514
16835228
18832655
19038973
19543507
19724923
20398908
20458727
20501643

Gene Ontology  (GO ID)

Biological Process

GO:0030183  B cell differentiation
GO:0007420  brain development
GO:0009790  embryonic development
GO:0008406  gonad development
GO:0007611  learning or memory
GO:0007399  nervous system development
GO:0007405  neuroblast proliferation
GO:0001944  vasculature development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0031527  filopodium membrane
GO:0016021  integral to membrane
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0004930  G-protein coupled receptor activity
GO:0030165  PDZ domain binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding