speckle-type POZ protein

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Synonym

Speckle-type POZ protein, SPOP, speckle-type POZ protein, TEF2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:126.80 cerebellum:176.30 brain stem:- corpus callosum/glia:87.50 pineal gland:148.30 peripheral nerve:153.40 spine:112.30 retina:- eye:135.20 artery/aorta:599.50 vein:266.60 lymphnode:70.80 peripheral blood:164 spleen:151.30 thymus:103.10 bone marrow:59 adipose:121 bone:38.40 skin:211.20
GeneChip cerebrum:7.64 cerebellum:8.28 brain stem:7.45 corpus callosum/glia:8.01 pineal gland:- peripheral nerve:7.90 spine:7.86 retina:- eye:- artery/aorta:8.55 vein:8.41 lymphnode:8.06 peripheral blood:- spleen:8.41 thymus:8.42 bone marrow:7.46 adipose:8 bone:- skin:7.51
CAGE cerebrum:3.98 cerebellum:- brain stem:3.94 corpus callosum/glia:4.05 pineal gland:3.88 peripheral nerve:- spine:3.83 retina:- eye:- artery/aorta:4.15 vein:3.86 lymphnode:3.63 peripheral blood:- spleen:3.74 thymus:4.02 bone marrow:- adipose:3.93 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:200.50 placenta:127.50 prostate:236.60 ovary:74.50 testis:73.50 heart:140.50 muscle:80.40 esophagus:342.80 stomach:148.70 intestine:129.60 colon:186.60     liver/hepato:42.20        lung:146.60    bladder:- kidney:187.10 pituitary:347.90 thyroid/parathyroid:163.70 adrenal gland:101.60 pancreas:26.70 breast:158 salivary:328.40
GeneChip uterus:8.56 placenta:7.51 prostate:8.97 ovary:8.19 testis:7.28 heart:7.83 muscle:7.63 esophagus:7.94 stomach:8.47 intestine:7.78 colon:7.51 liver/hepato:7.87 lung:8.04 bladder:- kidney:7.56 pituitary:8.05 thyroid/parathyroid:8.25 adrenal gland:8.06 pancreas:6.30 breast:8.23 salivary:8
CAGE uterus:4.31 placenta:3.61 prostate:3.94 ovary:3.89 testis:3.42 heart:3.65 muscle:3.31 esophagus:3.61 stomach:- intestine:3.70 colon:3.80     liver/hepato:3.56    lung:3.83 bladder:3.90 kidney:3.45 pituitary:4.03 thyroid/parathyroid:4.02 adrenal gland:- pancreas:3.65 breast:3.54 salivary:4.11
RNA-seq uterus:- placenta:- prostate:0.23 ovary:0.54 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.12        lung:0.00    bladder:- kidney:0.01 pituitary:- thyroid/parathyroid:0.20 adrenal gland:0.09 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001007226
Gene ID 8405
Unigene ID Hs.463382
Probe set ID 208927_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000121067
GTEx ID ENSG00000121067

Orthologous Gene

Mouse[11]  NM_025287, NM_207271, NM_148949, NM_207272, NM_001146107, NM_001163731, NM_207273, NM_001163730, NM_001034860, NM_001177694
Rat[4]  NM_001100496, NM_001100996, NM_001100985, NM_207272, NM_001146107, NM_001163731, NM_207273, NM_001163730, NM_001034860, NM_001177694

Chromosomal Region

17q21.33  [47,676,246  -  47,755,596]

Gene Family (Interpro ID)

IPR011333  BTB/POZ fold
IPR000210  BTB/POZ-like
IPR002083  MATH
IPR008974  TRAF-like

Link to Pubmed  (Pubmed ID)

8125298
8889548
9414087
10426994
11076863
11279055
12183056
12426564
12426565
12477932
12740575
14702039
15121856
15240113
15489334
15489336
15897469
16189514
16381901
16524876
16651542
16740475
17353931
18218622
18414007
18997279
19164706
19256485
19261606
19762545
19818708
20379614
21139048
21573799
21577200
21890473
21906983
21988832
22013077
22053931
22085717
22632832
22911784
23216165
23535732
23559371
23654205
23999291
24072710
24250222
24451148
24508459

Gene Ontology  (GO ID)

Biological Process

GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0016567  protein ubiquitination

Cellular Component

GO:0031463  Cul3-RING ubiquitin ligase complex
GO:0016607  nuclear speck
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0031625  ubiquitin protein ligase binding