MYST histone acetyltransferase 1

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Synonym

FLJ14040, MYST histone acetyltransferase 1, Probable histone acetyltransferase MYST1, PP7073, MYST protein 1, hMOF, MOF, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.10 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:122.70 spine:112.30 retina:- eye:88.20 artery/aorta:- vein:66.60 lymphnode:40.40 peripheral blood:18.20 spleen:18.90 thymus:- bone marrow:39.40 adipose:- bone:- skin:52.80
GeneChip cerebrum:7.01 cerebellum:7.21 brain stem:7.01 corpus callosum/glia:6.68 pineal gland:- peripheral nerve:6.88 spine:6.78 retina:- eye:- artery/aorta:7.03 vein:6.91 lymphnode:7.09 peripheral blood:- spleen:6.79 thymus:7.23 bone marrow:6.49 adipose:6.92 bone:- skin:7.14
CAGE cerebrum:4.11 cerebellum:- brain stem:3.85 corpus callosum/glia:3.90 pineal gland:3.93 peripheral nerve:- spine:3.98 retina:- eye:- artery/aorta:4.33 vein:4.33 lymphnode:4.11 peripheral blood:- spleen:3.95 thymus:4.18 bone marrow:- adipose:3.87 bone:- skin:-
RNA-seq cerebrum:3.52 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.21 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.72 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:32.80 prostate:78.90 ovary:37.30 testis:43.30 heart:51.10 muscle:100.50 esophagus:- stomach:21.20 intestine:- colon:101.80     liver/hepato:42.20        lung:34.20    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:9.30 salivary:-
GeneChip uterus:6.97 placenta:7.07 prostate:7.02 ovary:7.41 testis:7.55 heart:7.07 muscle:7.37 esophagus:6.75 stomach:6.65 intestine:6.90 colon:7.03 liver/hepato:6.86 lung:7.04 bladder:- kidney:6.79 pituitary:6.93 thyroid/parathyroid:7.11 adrenal gland:7.09 pancreas:6.42 breast:7.06 salivary:7.45
CAGE uterus:4.30 placenta:4.31 prostate:4.07 ovary:4.41 testis:4.24 heart:4.32 muscle:4.53 esophagus:3.76 stomach:- intestine:3.92 colon:4.36     liver/hepato:3.64    lung:4.30 bladder:3.97 kidney:3.94 pituitary:4.10 thyroid/parathyroid:4.33 adrenal gland:- pancreas:4.27 breast:4.37 salivary:4.61
RNA-seq uterus:- placenta:- prostate:4.55 ovary:4.74 testis:4.73 heart:3.45 muscle:4.37 esophagus:- stomach:- intestine:- colon:4.02     liver/hepato:2.97        lung:4.15    bladder:- kidney:3.63 pituitary:- thyroid/parathyroid:4.67 adrenal gland:4.21 pancreas:- breast:3.46 salivary:-

Gene Information

IDs

Refseq ID NM_032188
Gene ID 84148
Unigene ID Hs.533803
Probe set ID 221820_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000103510
GTEx ID ENSG00000103510

Orthologous Gene

Mouse[1]  NM_026370
Rat[1]  NM_001017378

Chromosomal Region

16p11.2  [31,127,075  -  31,142,714]

Gene Family (Interpro ID)

IPR000953  Chromo domain

Link to Pubmed  (Pubmed ID)

8125298
10786633
11742995
11965546
12397079
12477932
14702039
15342556
15489334
15498874
15923642
15960975
16024812
16096645
16227571
17182677
17189187
17694080
17967868
18058815
19578370
19766566
19854137
19913121
20018852
20224553
20360068
20479123
20628086
21217699
21321083
21502975
21691301
22020126
22152480
22586264
22918831
22939629
23602568
23628702
23638218
23863932
24126058
24163370
24837678

Gene Ontology  (GO ID)

Biological Process

GO:0016573  histone acetylation
GO:0043984  histone H4-K16 acetylation
GO:0043981  histone H4-K5 acetylation
GO:0043982  histone H4-K8 acetylation
GO:0030099  myeloid cell differentiation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000123  histone acetyltransferase complex
GO:0000776  kinetochore
GO:0071339  MLL1 complex
GO:0005634  nucleus

Molecular Function

GO:0016407  acetyltransferase activity
GO:0019899  enzyme binding
GO:0004402  histone acetyltransferase activity
GO:0046972  histone acetyltransferase activity (H4-K16 specific)
GO:0043995  histone acetyltransferase activity (H4-K5 specific)
GO:0043996  histone acetyltransferase activity (H4-K8 specific)
GO:0046872  metal ion binding
GO:0035064  methylated histone residue binding
GO:0005515  protein binding
GO:0008134  transcription factor binding