interferon induced transmembrane protein 1 (9-27)

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Synonym

Interferon-inducible protein 9-27, IFITM1, interferon induced transmembrane protein 1 (9-27), Leu-13 antigen, LEU13, CD225 antigen, 9-27, IFI17, CD225, Interferon-induced protein 17, Interferon-induced transmembrane protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:118.60 eye:146.90 artery/aorta:- vein:66.60 lymphnode:192.10 peripheral blood:182.20 spleen:75.60 thymus:25.80 bone marrow:669.10 adipose:121 bone:76.80 skin:196.80
GeneChip cerebrum:8.20 cerebellum:7.15 brain stem:8.38 corpus callosum/glia:8.21 pineal gland:- peripheral nerve:9.98 spine:9.05 retina:- eye:- artery/aorta:10.19 vein:10.06 lymphnode:10.53 peripheral blood:- spleen:11.15 thymus:9.88 bone marrow:9.19 adipose:10.49 bone:- skin:9.72
CAGE cerebrum:4.50 cerebellum:- brain stem:4.65 corpus callosum/glia:4.35 pineal gland:4.86 peripheral nerve:- spine:5.60 retina:- eye:- artery/aorta:5.55 vein:5.71 lymphnode:6.23 peripheral blood:- spleen:6.46 thymus:5.33 bone marrow:- adipose:6.18 bone:- skin:-
RNA-seq cerebrum:5.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:9.03 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:8.57 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:164 placenta:58.30 prostate:180.20 ovary:596.20 testis:26 heart:51.10 muscle:100.50 esophagus:- stomach:42.50 intestine:- colon:50.90     liver/hepato:42.20        lung:78.20    bladder:- kidney:10.40 pituitary:116 thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:44.50 breast:65.10 salivary:-
GeneChip uterus:10.56 placenta:8.42 prostate:9.94 ovary:10.93 testis:8.09 heart:10.20 muscle:8.15 esophagus:9.13 stomach:9.51 intestine:9.53 colon:10.29 liver/hepato:9.47 lung:10.01 bladder:- kidney:8.80 pituitary:8.40 thyroid/parathyroid:9.42 adrenal gland:9.77 pancreas:8.09 breast:9.99 salivary:8.26
CAGE uterus:5.58 placenta:5.09 prostate:5.46 ovary:6.35 testis:4.74 heart:5.72 muscle:5.12 esophagus:5.55 stomach:- intestine:5.02 colon:5.05     liver/hepato:5.12    lung:5.80 bladder:5.43 kidney:5.05 pituitary:4.69 thyroid/parathyroid:5.56 adrenal gland:- pancreas:4.47 breast:5.80 salivary:3.89
RNA-seq uterus:- placenta:- prostate:7.95 ovary:8.87 testis:8.02 heart:6.51 muscle:6.23 esophagus:- stomach:- intestine:- colon:8.07     liver/hepato:6.69        lung:8.75    bladder:- kidney:7.26 pituitary:- thyroid/parathyroid:7.03 adrenal gland:8.82 pancreas:- breast:7.17 salivary:-

Gene Information

IDs

Refseq ID NM_003641
Gene ID 8519
Unigene ID Hs.458414
Probe set ID 214022_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000185885
GTEx ID ENSG00000185885

Orthologous Gene

Mouse[5]  NM_001112715, NM_026820, NM_025378, NM_030694, NM_028968
Rat[1]  NM_001106314, NM_030833, NM_001136124, NM_030694, NM_028968

Chromosomal Region

11p15.5  [313,506  -  315,272]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1383329
2398277
2492664
3935435
6548414
7559564
12477932
12926988
14667819
15489334
15661263
15808405
18202764
18781797
18829488
19304549
19499152
19946888
20064371
20099975
20220060
20331378
20428811
20628624
20838853
20972266
21177806
21253575
21890473
21906983
21963094
21976647
22363774
22505724
22609115
22634173
22787204
22996292
23376165
23720721
23898208
24076421
24603679

Gene Ontology  (GO ID)

Biological Process

GO:0007166  cell surface receptor linked signal transduction
GO:0019221  cytokine-mediated signaling pathway
GO:0051607  defense response to virus
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0045071  negative regulation of viral genome replication
GO:0046597  negative regulation of virion penetration into host cell
GO:0001503  ossification
GO:0045669  positive regulation of osteoblast differentiation
GO:0050776  regulation of immune response
GO:0034341  response to interferon-gamma
GO:0009615  response to virus
GO:0060337  type I interferon-mediated signaling pathway

Cellular Component

GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding
GO:0005057  receptor signaling protein activity