eukaryotic translation initiation factor 4E binding protein 3

 jump to detail

Synonym

4E-BP3, eIF4E-binding protein 3, EIF4EBP3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.70 cerebellum:5.36 brain stem:5.79 corpus callosum/glia:6.11 pineal gland:- peripheral nerve:6.17 spine:6.59 retina:- eye:- artery/aorta:6.69 vein:6.61 lymphnode:6.89 peripheral blood:- spleen:7.07 thymus:6.69 bone marrow:6.48 adipose:7.08 bone:- skin:7.35
CAGE cerebrum:2.68 cerebellum:- brain stem:2.79 corpus callosum/glia:2.94 pineal gland:2.83 peripheral nerve:- spine:3.75 retina:- eye:- artery/aorta:3.63 vein:3.37 lymphnode:3.26 peripheral blood:- spleen:2.78 thymus:2.46 bone marrow:- adipose:3.62 bone:- skin:-
RNA-seq cerebrum:2.42 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.68 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.48 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:19.60    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:6.53 placenta:6.13 prostate:7.20 ovary:7.39 testis:7.54 heart:6.94 muscle:7.48 esophagus:7.30 stomach:6.74 intestine:6.65 colon:6.72 liver/hepato:6.84 lung:7.06 bladder:- kidney:7.19 pituitary:6.42 thyroid/parathyroid:7.32 adrenal gland:7.51 pancreas:6.71 breast:7.45 salivary:7.22
CAGE uterus:3.05 placenta:2.14 prostate:2.98 ovary:3.09 testis:3.86 heart:3.47 muscle:4.83 esophagus:3.48 stomach:- intestine:3.40 colon:4.05     liver/hepato:3.92    lung:3.52 bladder:3.46 kidney:3.17 pituitary:1.17 thyroid/parathyroid:3.47 adrenal gland:- pancreas:4.07 breast:3.81 salivary:4.20
RNA-seq uterus:- placenta:- prostate:4.46 ovary:3.56 testis:3.95 heart:3.00 muscle:6.04 esophagus:- stomach:- intestine:- colon:3.34     liver/hepato:3.47        lung:3.91    bladder:- kidney:3.95 pituitary:- thyroid/parathyroid:4.89 adrenal gland:4.25 pancreas:- breast:4.19 salivary:-

Gene Information

IDs

Refseq ID NM_003732
Gene ID 8637
Unigene ID Hs.594084
Probe set ID 214919_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000243056
GTEx ID ENSG00000243056

Orthologous Gene

Mouse[1]  NM_201256
Rat [0]  

Chromosomal Region

5q31.3  [139,927,251  -  139,929,163]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9593750
11865047
12477932
12482586
14507920
14557257
15153109
15489334
16189514
16271312
17316564
19615732
19946888
20621385
21088106
21145461
22684010

Gene Ontology  (GO ID)

Biological Process

GO:0045947  negative regulation of translational initiation

Cellular Component

GO:0016281  eukaryotic translation initiation factor 4F complex

Molecular Function

GO:0008190  eukaryotic initiation factor 4E binding
GO:0005515  protein binding
GO:0030371  translation repressor activity