forkhead box H1

 jump to detail

Synonym

Fast-1, FAST1, Fast-2, FAST2, FOXH1, Forkhead activin signal transducer 2, Forkhead box protein H1, Forkhead activin signal transducer 1, hFAST-1, FAST-1, forkhead box H1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.56 cerebellum:5.51 brain stem:5.70 corpus callosum/glia:5.44 pineal gland:- peripheral nerve:5.21 spine:5.38 retina:- eye:- artery/aorta:5.37 vein:5.52 lymphnode:5.26 peripheral blood:- spleen:4.97 thymus:5.18 bone marrow:5.52 adipose:5.38 bone:- skin:5.35
CAGE cerebrum:0.01 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.07 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:5.28 placenta:5.34 prostate:5.13 ovary:5.20 testis:5.41 heart:5.42 muscle:5.67 esophagus:5.25 stomach:5.37 intestine:5.55 colon:5.53 liver/hepato:5.52 lung:5.36 bladder:- kidney:5.49 pituitary:5.46 thyroid/parathyroid:5.16 adrenal gland:5.44 pancreas:5.43 breast:5.14 salivary:5.60
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0.32 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0.04     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.01 ovary:0.02 testis:0.29 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.13     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.03 pituitary:- thyroid/parathyroid:0.02 adrenal gland:0.09 pancreas:- breast:0.05 salivary:-

Gene Information

IDs

Refseq ID NM_003923
Gene ID 8928
Unigene ID -
Probe set ID 207644_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000160973
GTEx ID ENSG00000160973

Orthologous Gene

Mouse[2]  NM_007989
Rat [0]  

Chromosomal Region

8q24.3  [145,698,795  -  145,701,718]

Gene Family (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

9288972
9389648
9702198
9858566
10199400
10938097
11076863
11371641
12471260
12477932
12732634
15084259
15363409
15737749
15750622
15982639
16120611
16636667
16916642
17438144
17474147
17507406
18538293
18922797
19420158
19525021
19711044
20211142
20301702
20634891
21828274

Gene Ontology  (GO ID)

Biological Process

GO:0048318  axial mesoderm development
GO:0001568  blood vessel development
GO:0003215  cardiac right ventricle morphogenesis
GO:0042074  cell migration involved in gastrulation
GO:0035054  embryonic heart tube anterior/posterior pattern formation
GO:0021508  floor plate formation
GO:0003146  heart jogging
GO:0001947  heart looping
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0033147  negative regulation of estrogen receptor signaling pathway
GO:0003151  outflow tract morphogenesis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051090  regulation of transcription factor activity
GO:0003139  secondary heart field specification
GO:0010159  specification of organ position
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0003222  ventricular trabecular myocardium morphogenesis

Cellular Component

GO:0032444  activin responsive factor complex
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0050681  androgen receptor binding
GO:0070410  co-SMAD binding
GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0070412  R-SMAD binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding