DnaJ (Hsp40) homolog, subfamily A, member 3

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Synonym

TID1, DnaJ protein Tid-1, DnaJ (Hsp40) homolog, subfamily A, member 3, DNAJA3, Tumorous imaginal discs protein Tid56 homolog, hTid-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.44 cerebellum:7.44 brain stem:7.44 corpus callosum/glia:7.32 pineal gland:- peripheral nerve:7.47 spine:7.36 retina:- eye:- artery/aorta:7.34 vein:7.32 lymphnode:7.34 peripheral blood:- spleen:7.38 thymus:7.35 bone marrow:7.01 adipose:7.51 bone:- skin:7.37
CAGE cerebrum:3.75 cerebellum:- brain stem:3.72 corpus callosum/glia:3.73 pineal gland:3.56 peripheral nerve:- spine:3.75 retina:- eye:- artery/aorta:3.17 vein:3.49 lymphnode:3.64 peripheral blood:- spleen:3.48 thymus:3.51 bone marrow:- adipose:3.21 bone:- skin:-
RNA-seq cerebrum:3.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.51 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.56 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.27 placenta:7.43 prostate:7.42 ovary:7.47 testis:7.72 heart:7.61 muscle:8.54 esophagus:7.81 stomach:7.39 intestine:7.71 colon:7.56 liver/hepato:7.97 lung:7.10 bladder:- kidney:7.84 pituitary:7.49 thyroid/parathyroid:7.39 adrenal gland:7.76 pancreas:7.20 breast:7.49 salivary:7.56
CAGE uterus:3.37 placenta:3.61 prostate:3.51 ovary:3.55 testis:3.76 heart:4.07 muscle:4.64 esophagus:3.63 stomach:- intestine:3.60 colon:3.89     liver/hepato:4.63    lung:3.25 bladder:3.52 kidney:3.97 pituitary:3.38 thyroid/parathyroid:3.76 adrenal gland:- pancreas:3.89 breast:3.66 salivary:3.37
RNA-seq uterus:- placenta:- prostate:3.64 ovary:3.26 testis:3.35 heart:3.64 muscle:4.60 esophagus:- stomach:- intestine:- colon:2.97     liver/hepato:4.59        lung:2.58    bladder:- kidney:3.61 pituitary:- thyroid/parathyroid:3.78 adrenal gland:3.21 pancreas:- breast:2.88 salivary:-

Gene Information

IDs

Refseq ID NM_001135110
Gene ID 9093
Unigene ID -
Probe set ID 205963_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000103423
GTEx ID ENSG00000103423

Orthologous Gene

Mouse[4]  NM_001135112, NM_023646
Rat[2]  NM_001038595, NM_001038596

Chromosomal Region

16p13.3  [4,475,806  -  4,506,776]

Gene Family (Interpro ID)

IPR003095  Heat shock protein DnaJ
IPR015609  Molecular chaperone, heat shock protein, Hsp40, DnaJ

Link to Pubmed  (Pubmed ID)

8125298
9683573
10411904
11005857
11116152
11147971
11679576
11707338
11719219
11927590
12097419
12118383
12477932
12879007
14578343
14702039
14993262
15156195
15231748
15489334
15520177
15546961
15589840
15601829
15753086
15805242
15879105
16189514
16196087
16204048
16344560
16518412
16531398
16713569
17314511
17588722
18063578
18097612
18624398
19038220
19380743
19681071
19900451
19935715
20186120
20565727
20800603
20877624
21106534
21139048
21145461
21242965
21311096
21710689
21890473
21942715
22544056
22595283
22692211
22939629
23438482
23455924
23698466
23752268
23956138
24250222
24255178
24492964
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0006924  activation-induced cell death of T cells
GO:0007569  cell aging
GO:0009790  embryonic development
GO:0006264  mitochondrial DNA replication
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0008285  negative regulation of cell proliferation
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0006469  negative regulation of protein kinase activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007528  neuromuscular junction development
GO:0043065  positive regulation of apoptosis
GO:0031398  positive regulation of protein ubiquitination
GO:0042102  positive regulation of T cell proliferation
GO:0006457  protein folding
GO:0050821  protein stabilization
GO:0009408  response to heat
GO:0034341  response to interferon-gamma
GO:0071340  skeletal muscle nicotinic acetylcholine receptor clustering
GO:0007264  small GTPase mediated signal transduction
GO:0033077  T cell differentiation in the thymus

Cellular Component

GO:0005884  actin filament
GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0019897  extrinsic to plasma membrane
GO:0033256  I-kappaB/NF-kappaB complex
GO:0008385  IkappaB kinase complex
GO:0005759  mitochondrial matrix
GO:0042645  mitochondrial nucleoid
GO:0031594  neuromuscular junction
GO:0005634  nucleus
GO:0045211  postsynaptic membrane

Molecular Function

GO:0005524  ATP binding
GO:0031072  heat shock protein binding
GO:0005133  interferon-gamma receptor binding
GO:0046872  metal ion binding
GO:0051059  NF-kappaB binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0030971  receptor tyrosine kinase binding
GO:0005083  small GTPase regulator activity
GO:0008134  transcription factor binding
GO:0051082  unfolded protein binding