CD8a molecule

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Synonym

T-lymphocyte differentiation antigen T8/Leu-2, CD8a molecule, CD8a antigen, Leu2, CD8A, CD8

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:13

cerebellum:37.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:20.20

peripheral blood:200.40

spleen:1607

thymus:3220.90

bone marrow:-

adipose:80.70

bone:25.60

skin:4.80

GeneChip

cerebrum:5.68

cerebellum:5.57

brain stem:5.75

corpus callosum/glia:5.39

pineal gland:-

peripheral nerve:5.73

spine:5.77

retina:-

eye:-

artery/aorta:5.68

vein:5.85

lymphnode:6.95

peripheral blood:-

spleen:9.62

thymus:10.78

bone marrow:6.70

adipose:6.03

bone:-

skin:5.69

CAGE

cerebrum:0.38

cerebellum:-

brain stem:1.00

corpus callosum/glia:1.11

pineal gland:0.97

peripheral nerve:-

spine:1.27

retina:-

eye:-

artery/aorta:2.55

vein:4.99

lymphnode:4.10

peripheral blood:-

spleen:5.13

thymus:6.84

bone marrow:-

adipose:1.76

bone:-

skin:-

RNA-seq

cerebrum:0.18

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:10.90

prostate:101.40

ovary:-

testis:8.70

heart:-

muscle:-

esophagus:-

stomach:106.20

intestine:194.40

colon:-

liver/hepato:-

lung:53.80

bladder:125.60

kidney:-

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:44.50

breast:9.30

salivary:-

GeneChip

uterus:5.64

placenta:5.37

prostate:5.40

ovary:5.71

testis:5.18

heart:5.91

muscle:5.64

esophagus:5.75

stomach:6.65

intestine:6.27

colon:6.51

liver/hepato:6.26

lung:6.68

bladder:-

kidney:5.79

pituitary:5.53

thyroid/parathyroid:5.78

adrenal gland:5.76

pancreas:5.99

breast:5.85

salivary:5.73

CAGE

uterus:2.08

placenta:0.68

prostate:2.38

ovary:1.98

testis:1.04

heart:1.44

muscle:0.56

esophagus:2.11

stomach:-

intestine:3.96

colon:2.60

liver/hepato:1.90

lung:3.50

bladder:2.83

kidney:1.66

pituitary:0.62

thyroid/parathyroid:1.90

adrenal gland:-

pancreas:1.42

breast:1.16

salivary:2.53

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.00

testis:0.13

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.07

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0.05

pituitary:-

thyroid/parathyroid:0.02

adrenal gland:0.02

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_001145873
Gene ID	925
Unigene ID	Hs.85258
Probe set ID	205758_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000153563
GTEx ID	ENSG00000153563

Orthologous Gene

Mouse[4]	NM_001081110, NM_009857
Rat [0]

Chromosomal Region

2p11.2 [87,011,729 - 87,035,519]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_44 [21,683 - 28,792]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR013106	Immunoglobulin V-set
IPR003596	Immunoglobulin V-set, subgroup

Gene Ontology (GO ID)

Biological Process

GO:0019882	antigen processing and presentation
GO:0045065	cytotoxic T cell differentiation
GO:0051607	defense response to virus
GO:0006955	immune response
GO:0050850	positive regulation of calcium-mediated signaling
GO:0050776	regulation of immune response
GO:0042110	T cell activation
GO:0002456	T cell mediated immunity
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0009897	external side of plasma membrane
GO:0005576	extracellular region
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane
GO:0042101	T cell receptor complex

Molecular Function

GO:0015026	coreceptor activity
GO:0042288	MHC class I protein binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding

CD8a molecule

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function