ribosomal protein S6 kinase, 90kDa, polypeptide 5

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Synonym

Ribosomal protein S6 kinase alpha-5, RSKL, RSK-like protein kinase, RLPK, MGC1911, MSK1, MSPK1, ribosomal protein S6 kinase, 90kDa, polypeptide 5, RPS6KA5, 90 kDa ribosomal protein S6 kinase 5

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:46.20 cerebellum:37.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:118.60 eye:23.50 artery/aorta:30 vein:- lymphnode:80.90 peripheral blood:18.20 spleen:- thymus:38.70 bone marrow:118.10 adipose:- bone:12.80 skin:28.80
GeneChip cerebrum:7.25 cerebellum:8.39 brain stem:6.96 corpus callosum/glia:8.02 pineal gland:- peripheral nerve:6.72 spine:7.70 retina:- eye:- artery/aorta:5.58 vein:6.03 lymphnode:6.82 peripheral blood:- spleen:7.33 thymus:6.85 bone marrow:6.28 adipose:6.09 bone:- skin:6.19
CAGE cerebrum:3.38 cerebellum:- brain stem:3.33 corpus callosum/glia:3.42 pineal gland:2.63 peripheral nerve:- spine:3.49 retina:- eye:- artery/aorta:2.50 vein:2.46 lymphnode:2.63 peripheral blood:- spleen:2.20 thymus:2.44 bone marrow:- adipose:1.86 bone:- skin:-
RNA-seq cerebrum:2.64 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.08 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.93 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:54.60 prostate:22.50 ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:85 intestine:32.40 colon:42.40     liver/hepato:-        lung:24.40    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:37.20 salivary:-
GeneChip uterus:6.92 placenta:8.10 prostate:6.66 ovary:6.73 testis:5.71 heart:6.37 muscle:6.40 esophagus:7 stomach:7.15 intestine:6.26 colon:6.54 liver/hepato:5.20 lung:6.25 bladder:- kidney:5.51 pituitary:6.67 thyroid/parathyroid:6.78 adrenal gland:4.78 pancreas:5.34 breast:7.27 salivary:6.69
CAGE uterus:3.09 placenta:3.53 prostate:3.03 ovary:2.27 testis:2.17 heart:2.23 muscle:2.81 esophagus:3.02 stomach:- intestine:3.15 colon:3.18     liver/hepato:1.41    lung:2.51 bladder:3.18 kidney:1.55 pituitary:2.71 thyroid/parathyroid:1.85 adrenal gland:- pancreas:2.48 breast:2.53 salivary:2.78
RNA-seq uterus:- placenta:- prostate:3.17 ovary:1.35 testis:1.41 heart:1.82 muscle:1.96 esophagus:- stomach:- intestine:- colon:1.74     liver/hepato:0.27        lung:1.30    bladder:- kidney:0.65 pituitary:- thyroid/parathyroid:1.79 adrenal gland:1.21 pancreas:- breast:1.13 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0043990  histone H2A-S1 phosphorylation
GO:0043987  histone H3-S10 phosphorylation
GO:0043988  histone H3-S28 phosphorylation
GO:0016572  histone phosphorylation
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0070498  interleukin-1-mediated signaling pathway
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0001818  negative regulation of cytokine production
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048011  nerve growth factor receptor signaling pathway
GO:0032793  positive regulation of CREB transcription factor activity
GO:0035066  positive regulation of histone acetylation
GO:0033129  positive regulation of histone phosphorylation
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0007243  protein kinase cascade
GO:0006355  regulation of transcription, DNA-dependent
GO:0009605  response to external stimulus
GO:0006950  response to stress
GO:0051403  stress-activated MAPK cascade
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0000287  magnesium ion binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity