heart and neural crest derivatives expressed 1

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Synonym

heart and neural crest derivatives expressed 1, Thing1, Hxt, eHand, eHAND, HAND1, EHAND

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.66 cerebellum:4.51 brain stem:4.68 corpus callosum/glia:4.51 pineal gland:- peripheral nerve:4.64 spine:4.62 retina:- eye:- artery/aorta:5.14 vein:4.85 lymphnode:4.67 peripheral blood:- spleen:4.48 thymus:4.66 bone marrow:4.76 adipose:4.72 bone:- skin:4.77
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0.34 lymphnode:0 peripheral blood:- spleen:0 thymus:0.42 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.46 placenta:5.06 prostate:4.57 ovary:4.46 testis:4.66 heart:5.68 muscle:4.97 esophagus:4.61 stomach:4.56 intestine:5.77 colon:6.20 liver/hepato:4.74 lung:4.46 bladder:- kidney:4.75 pituitary:4.74 thyroid/parathyroid:4.38 adrenal gland:4.80 pancreas:5.22 breast:4.54 salivary:4.66
CAGE uterus:0 placenta:1.64 prostate:1.88 ovary:0 testis:0 heart:1.74 muscle:0 esophagus:0 stomach:- intestine:3.06 colon:3.34     liver/hepato:0    lung:0.18 bladder:2.29 kidney:0 pituitary:0.10 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:3.03 ovary:0.01 testis:0.14 heart:2.86 muscle:0 esophagus:- stomach:- intestine:- colon:4.43     liver/hepato:0        lung:0.06    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.08 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_004821
Gene ID 9421
Unigene ID Hs.152531
Probe set ID 220138_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000113196
GTEx ID ENSG00000113196

Orthologous Gene

Mouse[2]  NM_008213
Rat [0]  

Chromosomal Region

5q33.2  [153,854,532  -  153,857,824]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1182795
8012384
9337404
9931445
10189962
10611232
10837146
10924525
11802795
11812799
12477932
12858532
14636580
15489334
15509787
16043483
18276607
19060921
19586923
20398657
21350214
21519287
21561848
22032825
22043484
22323723
23292007
24182332

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0001824  blastocyst development
GO:0003218  cardiac left ventricle formation
GO:0003219  cardiac right ventricle formation
GO:0060411  cardiac septum morphogenesis
GO:0060536  cartilage morphogenesis
GO:0035050  embryonic heart tube development
GO:0003144  embryonic heart tube formation
GO:0007507  heart development
GO:0001947  heart looping
GO:0060485  mesenchyme development
GO:0001707  mesoderm formation
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0042475  odontogenesis of dentine-containing tooth
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006366  transcription from RNA polymerase II promoter
GO:0001829  trophectodermal cell differentiation
GO:0060707  trophoblast giant cell differentiation
GO:0055010  ventricular cardiac muscle tissue morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0043425  bHLH transcription factor binding
GO:0044212  DNA regulatory region binding
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding