nuclear receptor co-repressor 1

Synonym

hCIT529I10, KIAA1047, N-CoR1, MGC104216, N-CoR, hN-CoR, NCOR1, nuclear receptor co-repressor 1, Nuclear receptor corepressor 1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:74.70

cerebellum:88.20

brain stem:-

corpus callosum/glia:58.30

pineal gland:148.30

peripheral nerve:92

spine:-

retina:118.60

eye:111.70

artery/aorta:119.90

vein:-

lymphnode:70.80

peripheral blood:109.30

spleen:18.90

thymus:116

bone marrow:216.50

adipose:121

bone:51.20

skin:120

GeneChip

cerebrum:6.92

cerebellum:6.82

brain stem:6.63

corpus callosum/glia:6.90

pineal gland:-

peripheral nerve:6.76

spine:6.65

retina:-

eye:-

artery/aorta:6.92

vein:6.83

lymphnode:7.16

peripheral blood:-

spleen:7.33

thymus:7.82

bone marrow:7.36

adipose:7.03

bone:-

skin:6.99

CAGE

cerebrum:3.82

cerebellum:-

brain stem:3.79

corpus callosum/glia:3.75

pineal gland:4.21

peripheral nerve:-

spine:3.97

retina:-

eye:-

artery/aorta:3.92

vein:3.83

lymphnode:3.69

peripheral blood:-

spleen:3.86

thymus:4.19

bone marrow:-

adipose:3.71

bone:-

skin:-

RNA-seq

cerebrum:2.75

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.16

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.12

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:94.70

prostate:101.40

ovary:186.30

testis:103.80

heart:114.90

muscle:40.20

esophagus:-

stomach:382.40

intestine:97.20

colon:262.90

liver/hepato:105.60

lung:112.40

bladder:-

kidney:145.60

pituitary:232

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:-

breast:120.80

salivary:-

GeneChip

uterus:7.35

placenta:6.89

prostate:7.49

ovary:7.25

testis:7.53

heart:6.87

muscle:6.88

esophagus:7.17

stomach:7.25

intestine:7.10

colon:7.10

liver/hepato:7.59

lung:7.27

bladder:-

kidney:7.22

pituitary:7.08

thyroid/parathyroid:6.96

adrenal gland:7.08

pancreas:6.44

breast:7.17

salivary:6.79

CAGE

uterus:3.82

placenta:3.59

prostate:3.64

ovary:3.83

testis:3.91

heart:3.62

muscle:3.98

esophagus:3.53

stomach:-

intestine:4.30

colon:4.10

liver/hepato:4.02

lung:3.79

bladder:3.71

kidney:3.72

pituitary:4.13

thyroid/parathyroid:3.54

adrenal gland:-

pancreas:3.63

breast:4.07

salivary:2.63

RNA-seq

uterus:-

placenta:-

prostate:3.27

ovary:3.61

testis:3.54

heart:2.31

muscle:3.14

esophagus:-

stomach:-

intestine:-

colon:3.24

liver/hepato:2.45

lung:2.65

bladder:-

kidney:3.31

pituitary:-

thyroid/parathyroid:3.15

adrenal gland:2.97

pancreas:-

breast:2.74

salivary:-

IDs

Refseq ID	NM_006311
Gene ID	9611
Unigene ID	Hs.462323
Probe set ID	200857_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000141027
GTEx ID	ENSG00000141027

Orthologous Gene

Mouse[6]	NM_011308
Rat[6]	NM_011308

Chromosomal Region

17p11.2 [15,934,718 - 16,119,010]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR009057	Homeodomain-like
IPR012287	Homeodomain-related
IPR017877	MYB-like
IPR001005	SANT, DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0044255	cellular lipid metabolic process
GO:0042632	cholesterol homeostasis
GO:0016568	chromatin modification
GO:0032922	circadian regulation of gene expression
GO:0060318	definitive erythrocyte differentiation
GO:0010467	gene expression
GO:0046329	negative regulation of JNK cascade
GO:0014067	negative regulation of phosphoinositide 3-kinase cascade
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0007219	Notch signaling pathway
GO:0031065	positive regulation of histone deacetylation
GO:0040014	regulation of multicellular organism growth
GO:0051225	spindle assembly
GO:0021794	thalamus development
GO:0006366	transcription from RNA polymerase II promoter
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006351	transcription, DNA-dependent
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0000118	histone deacetylase complex
GO:0000790	nuclear chromatin
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0016580	Sin3 complex
GO:0005876	spindle microtubule
GO:0005667	transcription factor complex
GO:0017053	transcriptional repressor complex

Molecular Function

GO:0003682	chromatin binding
GO:0044212	DNA regulatory region binding
GO:0042826	histone deacetylase binding
GO:0035033	histone deacetylase regulator activity
GO:0005515	protein binding
GO:0046965	retinoid X receptor binding
GO:0043565	sequence-specific DNA binding
GO:0046966	thyroid hormone receptor binding
GO:0003714	transcription corepressor activity
GO:0003700	transcription factor activity

nuclear receptor co-repressor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function