CD59 molecule, complement regulatory protein

Synonym

MACIF, Membrane attack complex inhibition factor, MAC-inhibitory protein, Membrane inhibitor of reactive lysis, MIN2, PROTECTIN, MIN3, HRF-20, 16.3A5, MSK21, EJ16, HRF20, EL32, CD59, G344, CD59 molecule, complement regulatory protein, MIC11, MEM43 antigen, MIN1, 20 kDa homologous restriction factor, Protectin, 1F5 antigen, MAC-IP, CD59 glycoprotein precursor, MGC2354, MIRL, EJ30, p18-20

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:311.70

cerebellum:831.20

brain stem:-

corpus callosum/glia:379.10

pineal gland:296.70

peripheral nerve:582.80

spine:673.80

retina:118.60

eye:276.20

artery/aorta:1049.10

vein:733.10

lymphnode:121.30

peripheral blood:692.30

spleen:132.30

thymus:180.40

bone marrow:137.80

adipose:685.70

bone:972.40

skin:700.80

GeneChip

cerebrum:8.86

cerebellum:8.82

brain stem:9.37

corpus callosum/glia:8.23

pineal gland:-

peripheral nerve:10.70

spine:9.18

retina:-

eye:-

artery/aorta:9.44

vein:9.95

lymphnode:8.56

peripheral blood:-

spleen:8.04

thymus:8.33

bone marrow:8.54

adipose:9.70

bone:-

skin:9.58

CAGE

cerebrum:5.19

cerebellum:-

brain stem:5.26

corpus callosum/glia:4.82

pineal gland:5.52

peripheral nerve:-

spine:5.25

retina:-

eye:-

artery/aorta:5.80

vein:5.14

lymphnode:5.31

peripheral blood:-

spleen:4.89

thymus:4.22

bone marrow:-

adipose:6.24

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.09

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:565

placenta:1435.40

prostate:180.20

ovary:596.20

testis:225

heart:740.80

muscle:462.10

esophagus:1371.30

stomach:191.20

intestine:421.20

colon:220.50

liver/hepato:211.10

lung:503.40

bladder:1633

kidney:561.40

pituitary:116

thyroid/parathyroid:818.70

adrenal gland:457.10

pancreas:284.50

breast:752.70

salivary:328.40

GeneChip

uterus:9.33

placenta:10.48

prostate:9.50

ovary:9.65

testis:8.03

heart:9.62

muscle:9.83

esophagus:9.29

stomach:9.24

intestine:9.26

colon:8.70

liver/hepato:8.11

lung:10.02

bladder:-

kidney:9.64

pituitary:9.45

thyroid/parathyroid:9.52

adrenal gland:9.12

pancreas:8.86

breast:9.86

salivary:9.87

CAGE

uterus:5.51

placenta:7.21

prostate:5.56

ovary:5.31

testis:4.93

heart:6.10

muscle:5.63

esophagus:5.87

stomach:-

intestine:4.56

colon:5.05

liver/hepato:5.58

lung:6.06

bladder:5.59

kidney:6.22

pituitary:5.53

thyroid/parathyroid:6.02

adrenal gland:-

pancreas:5.51

breast:6.00

salivary:6.32

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.15

testis:0.00

heart:0.04

muscle:0.70

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.30

lung:1.10

bladder:-

kidney:0.04

pituitary:-

thyroid/parathyroid:0.35

adrenal gland:0.55

pancreas:-

breast:0.28

salivary:-

IDs

Refseq ID	NM_203330
Gene ID	966
Unigene ID	Hs.278573
Probe set ID	200985_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000085063
GTEx ID	ENSG00000085063

Orthologous Gene

Mouse[5]	NM_001111060, NM_007652, NM_181858
Rat[5]	NM_001111060, NM_007652, NM_181858

Chromosomal Region

11p13 [33,719,807 - 33,757,991]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_41 [5,000 - 38,469]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016054

Ly-6 antigen / uPA receptor -like

GO:0007596	blood coagulation
GO:0007166	cell surface receptor linked signal transduction
GO:0045087	innate immune response
GO:0001971	negative regulation of activation of membrane attack complex
GO:0043066	negative regulation of apoptosis
GO:0042102	positive regulation of T cell proliferation
GO:0030449	regulation of complement activation

GO:0031362	anchored to external side of plasma membrane
GO:0009986	cell surface
GO:0043218	compact myelin
GO:0005615	extracellular space
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0042383	sarcolemma

GO:0001848	complement binding
GO:0005515	protein binding

CD59 molecule, complement regulatory protein

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function