zinc finger E-box binding homeobox 2

Synonym

ZFX1B, zinc finger homeobox 1b, SIP-1, KIAA0569, SMADIP1, ZEB2, HRIHFB2411, Zinc finger homeobox protein 1b, ZFHX1B, Smad-interacting protein 1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:40.30

bone:25.60

skin:14.40

GeneChip

cerebrum:7.38

cerebellum:4.08

brain stem:7.50

corpus callosum/glia:8.36

pineal gland:-

peripheral nerve:7.62

spine:8.25

retina:-

eye:-

artery/aorta:6.74

vein:6.50

lymphnode:5.61

peripheral blood:-

spleen:7.02

thymus:4.35

bone marrow:5.87

adipose:6.79

bone:-

skin:5.27

CAGE

cerebrum:5.24

cerebellum:-

brain stem:5.77

corpus callosum/glia:6.42

pineal gland:4.38

peripheral nerve:-

spine:5.98

retina:-

eye:-

artery/aorta:4.69

vein:4.72

lymphnode:4.70

peripheral blood:-

spleen:5.35

thymus:3.05

bone marrow:-

adipose:5.50

bone:-

skin:-

RNA-seq

cerebrum:4.54

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.56

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.12

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:-

prostate:11.30

ovary:-

testis:38.90

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:64.80

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:6.37

placenta:5.56

prostate:5.21

ovary:5.97

testis:4.68

heart:6.25

muscle:4.79

esophagus:4.38

stomach:5.60

intestine:5.20

colon:5.45

liver/hepato:4.62

lung:6.56

bladder:-

kidney:4.44

pituitary:3.21

thyroid/parathyroid:4.68

adrenal gland:6.63

pancreas:3.01

breast:5.87

salivary:3.74

CAGE

uterus:4.95

placenta:4.42

prostate:4.72

ovary:5.19

testis:4.28

heart:4.86

muscle:3.53

esophagus:4.36

stomach:-

intestine:4.02

colon:4.07

liver/hepato:3.64

lung:5.24

bladder:4.87

kidney:4.14

pituitary:2.79

thyroid/parathyroid:3.49

adrenal gland:-

pancreas:2.81

breast:5.20

salivary:2.90

RNA-seq

uterus:-

placenta:-

prostate:3.51

ovary:4.53

testis:3.83

heart:3.16

muscle:0.39

esophagus:-

stomach:-

intestine:-

colon:3.25

liver/hepato:1.53

lung:3.50

bladder:-

kidney:2.29

pituitary:-

thyroid/parathyroid:2.46

adrenal gland:3.95

pancreas:-

breast:4.10

salivary:-

IDs

Refseq ID	NM_014795
Gene ID	9839
Unigene ID	Hs.348711
Probe set ID	203603_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000169554
GTEx ID	ENSG00000169554

Orthologous Gene

Mouse[1]	NM_015753
Rat[1]	NM_001033701

Chromosomal Region

2q22.3 [145,121,063 - 145,282,147]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related
IPR015880	Zinc finger, C2H2-like
IPR007087	Zinc finger, C2H2-type

GO:0021846	cell proliferation in forebrain
GO:0021766	hippocampus development
GO:0007399	nervous system development
GO:0001755	neural crest cell migration
GO:0001843	neural tube closure
GO:0043507	positive regulation of JUN kinase activity
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0001756	somitogenesis
GO:0006351	transcription, DNA-dependent

GO:0005737	cytoplasm
GO:0005730	nucleolus
GO:0005634	nucleus

GO:0046872	metal ion binding
GO:0019208	phosphatase regulator activity
GO:0070412	R-SMAD binding
GO:0043565	sequence-specific DNA binding
GO:0046332	SMAD binding
GO:0003700	transcription factor activity

zinc finger E-box binding homeobox 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function