GRB2-associated binding protein 2

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Synonym

pp100, GRB2-associated-binding protein 2, GRB2-associated binding protein 2, KIAA0571, GAB2, GRB2-associated binder 2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:37.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:148.30

peripheral nerve:30.70

spine:-

retina:118.60

eye:41.10

artery/aorta:-

vein:133.30

lymphnode:30.30

peripheral blood:36.40

spleen:75.60

thymus:51.50

bone marrow:157.40

adipose:-

bone:12.80

skin:43.20

GeneChip

cerebrum:8.29

cerebellum:7.03

brain stem:8.51

corpus callosum/glia:9.41

pineal gland:-

peripheral nerve:7.49

spine:8.78

retina:-

eye:-

artery/aorta:7.69

vein:7.75

lymphnode:6.75

peripheral blood:-

spleen:6.96

thymus:7.43

bone marrow:7.06

adipose:7.59

bone:-

skin:7.36

CAGE

cerebrum:3.81

cerebellum:-

brain stem:4.46

corpus callosum/glia:5.22

pineal gland:2.49

peripheral nerve:-

spine:4.40

retina:-

eye:-

artery/aorta:4.24

vein:3.44

lymphnode:3.10

peripheral blood:-

spleen:3.46

thymus:3.45

bone marrow:-

adipose:3.95

bone:-

skin:-

RNA-seq

cerebrum:2.69

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.59

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.16

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:109.30

prostate:11.30

ovary:149.10

testis:30.30

heart:38.30

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:67.80

liver/hepato:-

lung:39.10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:158

salivary:-

GeneChip

uterus:7.39

placenta:7.53

prostate:6.45

ovary:7.78

testis:6.47

heart:7.01

muscle:6.50

esophagus:6.94

stomach:6.73

intestine:6.88

colon:7.29

liver/hepato:6.32

lung:7.48

bladder:-

kidney:6.41

pituitary:6.92

thyroid/parathyroid:6.45

adrenal gland:6.73

pancreas:6.54

breast:7.39

salivary:6.10

CAGE

uterus:3.86

placenta:3.76

prostate:3.39

ovary:3.71

testis:2.75

heart:3.58

muscle:2.61

esophagus:3.10

stomach:-

intestine:3.19

colon:3.45

liver/hepato:2.05

lung:3.89

bladder:3.63

kidney:2.48

pituitary:3.11

thyroid/parathyroid:2.58

adrenal gland:-

pancreas:2.48

breast:3.95

salivary:2.72

RNA-seq

uterus:-

placenta:-

prostate:2.68

ovary:2.89

testis:2.26

heart:0.90

muscle:0.28

esophagus:-

stomach:-

intestine:-

colon:1.62

liver/hepato:0.00

lung:3.02

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:1.18

adrenal gland:1.26

pancreas:-

breast:1.74

salivary:-

IDs

Refseq ID	NM_080491
Gene ID	9846
Unigene ID	Hs.429434
Probe set ID	203853_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000033327
GTEx ID	ENSG00000033327

Orthologous Gene

Mouse [0]
Rat [0]

Chromosomal Region

11q14.1 [77,926,343 - 78,129,394]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001849

Pleckstrin homology

GO:0045087	innate immune response
GO:0030316	osteoclast differentiation
GO:0048015	phosphoinositide-mediated signaling
GO:0008284	positive regulation of cell proliferation
GO:0043306	positive regulation of mast cell degranulation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane

GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
GO:0005515	protein binding
GO:0005070	SH3/SH2 adaptor activity
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor protein activity

GRB2-associated binding protein 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function