WD repeat domain 1

 jump to detail

Synonym

WDR1, WD repeat protein 1, WD repeat domain 1, Actin-interacting protein 1, NORI-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:175.40 cerebellum:50.40 brain stem:- corpus callosum/glia:1983 pineal gland:- peripheral nerve:276 spine:224.60 retina:118.60 eye:205.70 artery/aorta:1199 vein:333.20 lymphnode:293.20 peripheral blood:346.20 spleen:510.50 thymus:747.30 bone marrow:314.90 adipose:161.30 bone:601.40 skin:566.40
GeneChip cerebrum:7.10 cerebellum:6.53 brain stem:7.20 corpus callosum/glia:7.33 pineal gland:- peripheral nerve:8.02 spine:7.65 retina:- eye:- artery/aorta:8.92 vein:8.78 lymphnode:8.45 peripheral blood:- spleen:8.10 thymus:9.23 bone marrow:8.62 adipose:8.30 bone:- skin:8.50
CAGE cerebrum:3.90 cerebellum:- brain stem:4.04 corpus callosum/glia:4.38 pineal gland:4.94 peripheral nerve:- spine:4.22 retina:- eye:- artery/aorta:5.48 vein:5.10 lymphnode:5.06 peripheral blood:- spleen:4.93 thymus:5.20 bone marrow:- adipose:4.83 bone:- skin:-
RNA-seq cerebrum:4.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.02 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.15 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:428.30 placenta:156.70 prostate:135.20 ovary:335.40 testis:199 heart:166 muscle:40.20 esophagus:342.80 stomach:573.50 intestine:486 colon:449.40     liver/hepato:84.40        lung:263.90    bladder:628.10 kidney:187.10 pituitary:- thyroid/parathyroid:1965 adrenal gland:- pancreas:53.30 breast:223 salivary:-
GeneChip uterus:8.73 placenta:8.25 prostate:8.68 ovary:8.45 testis:9.87 heart:7.99 muscle:7.71 esophagus:8.97 stomach:8.20 intestine:8.33 colon:8.75 liver/hepato:7.23 lung:8.58 bladder:- kidney:8.27 pituitary:7.36 thyroid/parathyroid:8.31 adrenal gland:7.50 pancreas:7.31 breast:8.31 salivary:8.04
CAGE uterus:5.29 placenta:4.73 prostate:5.02 ovary:5.06 testis:4.89 heart:4.81 muscle:4.47 esophagus:5.19 stomach:- intestine:5.05 colon:5.10     liver/hepato:4.66    lung:4.88 bladder:5.36 kidney:5.07 pituitary:4.03 thyroid/parathyroid:4.93 adrenal gland:- pancreas:4.01 breast:4.81 salivary:4.75
RNA-seq uterus:- placenta:- prostate:6.86 ovary:6.42 testis:6.27 heart:4.99 muscle:4.98 esophagus:- stomach:- intestine:- colon:6.16     liver/hepato:4.81        lung:6.59    bladder:- kidney:6.09 pituitary:- thyroid/parathyroid:6.60 adrenal gland:6.58 pancreas:- breast:5.31 salivary:-

Gene Information

IDs

Refseq ID NM_017491
Gene ID 9948
Unigene ID Hs.128548
Probe set ID 200611_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000071127
GTEx ID ENSG00000071127

Orthologous Gene

Mouse[9]  NM_011715
Rat[1]  NM_001014135

Chromosomal Region

4p16.1  [10,075,963  -  10,118,573]

Gene Family (Interpro ID)

IPR020472  G-protein beta WD-40 repeat, region
IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

1602151
6457647
8125298
10036186
10366597
12477932
12665801
14630798
15231747
15489334
15592455
15629458
16009940
17293856
18179892
18494608
18624398
18781797
19056867
19165527
19818632
20631256
21139048
21294900
21319273
21890473
21900206
21906983
21943158
21963094
22229870
22505724
22863883
22939629
23000965
23215816
23293323
23382044
23524849
23707566
23824909
24250222
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0007605  sensory perception of sound

Cellular Component

GO:0030054  cell junction
GO:0042995  cell projection
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0002102  podosome

Molecular Function

GO:0003779  actin binding