nuclear receptor subfamily 1, group D, member 2

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Synonym

Orphan nuclear hormone receptor BD73, nuclear receptor subfamily 1, group D, member 2, RVR, EAR-1R, BD73, Rev-erb-beta, NR1D2, EAR-1r, Orphan nuclear receptor NR1D2, Hs.37288

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:45 cerebellum:75.60 brain stem:- corpus callosum/glia:116.60 pineal gland:296.70 peripheral nerve:92 spine:224.60 retina:- eye:117.50 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:18.20 spleen:- thymus:25.80 bone marrow:- adipose:40.30 bone:25.60 skin:14.40
GeneChip cerebrum:7.34 cerebellum:7.94 brain stem:7.18 corpus callosum/glia:7.46 pineal gland:- peripheral nerve:7.06 spine:7.40 retina:- eye:- artery/aorta:5.99 vein:6.45 lymphnode:6.41 peripheral blood:- spleen:7.08 thymus:6.57 bone marrow:5.12 adipose:6.50 bone:- skin:6.45
CAGE cerebrum:3.97 cerebellum:- brain stem:3.86 corpus callosum/glia:3.78 pineal gland:4.65 peripheral nerve:- spine:3.73 retina:- eye:- artery/aorta:3.79 vein:3.45 lymphnode:3.17 peripheral blood:- spleen:3.19 thymus:2.76 bone marrow:- adipose:3.54 bone:- skin:-
RNA-seq cerebrum:4.77 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.97 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:80.10 prostate:11.30 ovary:37.30 testis:30.30 heart:63.90 muscle:60.30 esophagus:- stomach:- intestine:32.40 colon:33.90     liver/hepato:84.40        lung:19.60    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:327.50 adrenal gland:50.80 pancreas:62.20 breast:9.30 salivary:-
GeneChip uterus:7.48 placenta:6.34 prostate:7.38 ovary:7.48 testis:5.69 heart:6.91 muscle:8.02 esophagus:6.64 stomach:7 intestine:6.50 colon:6.10 liver/hepato:6.39 lung:6.85 bladder:- kidney:6.57 pituitary:6.51 thyroid/parathyroid:7.81 adrenal gland:6.38 pancreas:6.53 breast:6.71 salivary:6.91
CAGE uterus:4.10 placenta:3.36 prostate:3.90 ovary:3.77 testis:2.86 heart:3.47 muscle:3.81 esophagus:3.58 stomach:- intestine:3.27 colon:3.54     liver/hepato:3.29    lung:3.29 bladder:3.56 kidney:2.42 pituitary:3.39 thyroid/parathyroid:4.28 adrenal gland:- pancreas:3.61 breast:3.69 salivary:3.82
RNA-seq uterus:- placenta:- prostate:4.20 ovary:4.48 testis:3.98 heart:3.98 muscle:4.22 esophagus:- stomach:- intestine:- colon:3.88     liver/hepato:1.62        lung:3.17    bladder:- kidney:3.02 pituitary:- thyroid/parathyroid:4.89 adrenal gland:4.46 pancreas:- breast:4.69 salivary:-

Gene Information

IDs

Refseq ID NM_001145425
Gene ID 9975
Unigene ID Hs.37288
Probe set ID 209750_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000174738
GTEx ID ENSG00000174738

Orthologous Gene

Mouse[2]  NM_011584
Rat[2]  NM_011584

Chromosomal Region

3p24.2  [23,986,751  -  24,021,237]

Gene Family (Interpro ID)

IPR001723  Steroid hormone receptor
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

7997240
8948627
9482666
9611234
10198169
11113208
12477932
15489334
15604093
16741567
17463251
17870090
17892483
17996965
18037887
18218725
18454201
20348464
21123168
21906983
22828941
23455924
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0010467  gene expression
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0006355  regulation of transcription, DNA-dependent
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0004879  ligand-dependent nuclear receptor activity
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0008270  zinc ion binding