SMEK homolog 2, suppressor of mek1 (Dictyostelium)

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Synonym

mKIAA1387, Smek2, KIAA1387, AW557776, SMEK homolog 2, suppressor of mek1 (Dictyostelium), AW011752

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:126.80 cerebellum:202.60 brain stem:190.70 corpus callosum/glia:- pineal gland:- peripheral nerve:152.90 spine:94.60 retina:192.90 eye:106.40 artery/aorta:168.80 vein:- lymphnode:108 peripheral blood:517.60 spleen:237 thymus:118.60 bone marrow:38.50 adipose:425.40 bone:125.20 skin:142.50
GeneChip cerebrum:8.61 cerebellum:9.04 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.40 spine:8.19 retina:8.44 eye:8.38 artery/aorta:- vein:9.17 lymphnode:10 peripheral blood:- spleen:10.02 thymus:- bone marrow:9.90 adipose:9.07 bone:9.95 skin:9.57
CAGE cerebrum:3.51 cerebellum:- brain stem:3.09 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.12 retina:- eye:- artery/aorta:3.74 vein:- lymphnode:4.46 peripheral blood:- spleen:3.76 thymus:4.05 bone marrow:- adipose:- bone:3.62 skin:3.86
RNA-seq cerebrum:1.33 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:218.10 placenta:138.10 prostate:92.60 ovary:149.40 testis:118.20 heart:37.20 muscle:71 esophagus:- stomach:- intestine:- colon:88.10     liver/hepato:18.10        lung:50.20    bladder:132.40 kidney:145.10 pituitary:180.80 thyroid/parathyroid:112.50 adrenal gland:- pancreas:75.10 breast:88.20 salivary:-
GeneChip uterus:9.32 placenta:9.26 prostate:8.73 ovary:9.46 testis:9.27 heart:8.35 muscle:8.53 esophagus:- stomach:9.03 intestine:9.39 colon:- liver/hepato:9.27 lung:9.24 bladder:9.31 kidney:8.96 pituitary:9.33 thyroid/parathyroid:- adrenal gland:9.26 pancreas:8.70 breast:8.97 salivary:8.82
CAGE uterus:3.72 placenta:3.51 prostate:3.64 ovary:3.63 testis:4.46 heart:- muscle:- esophagus:- stomach:3.39 intestine:3.83 colon:3.81     liver/hepato:3.41    lung:3.70 bladder:3.56 kidney:- pituitary:3.59 thyroid/parathyroid:- adrenal gland:3.64 pancreas:3.61 breast:3.62 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.42 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.53        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_134034
Gene ID 104570
Unigene ID Mm.276386
Probe set ID 1450901_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020463

Orthologous Gene

Human[2]  NM_001122964, NM_020463
Rat[1]  NM_001108367, NM_020463

Chromosomal Region

11A3.3  [29,072,890  -  29,120,797]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10725249
10922068
11042159
11076861
11217851
12466851
12477932
12520002
14610273
14621295
15489334
15782199
16141072
16141073
16602821
17967808
18287559
20876121
21386911
21423269
21652651

Gene Ontology  (GO ID)

Biological Process

GO:0045722  positive regulation of gluconeogenesis
GO:0006470  protein amino acid dephosphorylation
GO:0019216  regulation of lipid metabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005634  nucleus
GO:0030289  protein phosphatase 4 complex

Molecular Function

GO:0005515  protein binding