thioredoxin domain containing 5

 jump to detail

Synonym

ERp46, PC-TRP, Thioredoxin domain-containing protein 5 precursor, thioredoxin domain containing 5, Tlp46, Txndc5, AL022641, Endoplasmic reticulum protein ERp46, Thioredoxin-like protein p46, Plasma cell-specific thioredoxin-related protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:85.10 cerebellum:73.70 brain stem:158.90 corpus callosum/glia:- pineal gland:515.60 peripheral nerve:133.80 spine:47.30 retina:96.40 eye:60.80 artery/aorta:168.80 vein:- lymphnode:43.20 peripheral blood:71.90 spleen:79 thymus:49.40 bone marrow:76.90 adipose:425.40 bone:187.90 skin:158.40
GeneChip cerebrum:8.76 cerebellum:8.23 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.09 spine:9.01 retina:8.43 eye:8.60 artery/aorta:- vein:10.41 lymphnode:10.36 peripheral blood:- spleen:10.49 thymus:- bone marrow:8.97 adipose:9.43 bone:9.04 skin:8.42
CAGE cerebrum:2.86 cerebellum:- brain stem:3.17 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.22 retina:- eye:- artery/aorta:3.87 vein:- lymphnode:4.47 peripheral blood:- spleen:5.07 thymus:3.14 bone marrow:- adipose:- bone:3.91 skin:4.18
RNA-seq cerebrum:11.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:193.30 prostate:61.80 ovary:356.20 testis:81.30 heart:18.60 muscle:213 esophagus:- stomach:392.70 intestine:110.90 colon:334.80     liver/hepato:108.60        lung:180.80    bladder:198.50 kidney:56.40 pituitary:38.80 thyroid/parathyroid:224.90 adrenal gland:- pancreas:206.40 breast:261.20 salivary:594
GeneChip uterus:10.88 placenta:9.86 prostate:10.53 ovary:10.85 testis:8.68 heart:8.98 muscle:9.18 esophagus:- stomach:10.90 intestine:11.36 colon:- liver/hepato:10.99 lung:10.45 bladder:10.06 kidney:9.44 pituitary:10.77 thyroid/parathyroid:- adrenal gland:9.85 pancreas:9.33 breast:9.45 salivary:11.41
CAGE uterus:4.64 placenta:4.45 prostate:4.71 ovary:4.61 testis:2.60 heart:- muscle:- esophagus:- stomach:5.05 intestine:5.08 colon:5.48     liver/hepato:5.32    lung:4.28 bladder:4.22 kidney:- pituitary:4.31 thyroid/parathyroid:- adrenal gland:4.53 pancreas:4.72 breast:4.19 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:4.85 esophagus:- stomach:- intestine:- colon:-     liver/hepato:21.57        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_145367
Gene ID 105245
Unigene ID Mm.28622
Probe set ID 1451091_at  [Mouse430_2]
Ensembl ID ENSMUSG00000038991

Orthologous Gene

Human[2]  NM_001145549, NM_030810
Rat[2]  NM_001145549, NM_030810

Chromosomal Region

-

Gene Family (Interpro ID)

IPR005788  Disulphide isomerase
IPR013766  Thioredoxin domain
IPR012335  Thioredoxin fold
IPR017936  Thioredoxin-like
IPR012336  Thioredoxin-like fold

Link to Pubmed  (Pubmed ID)

7671812
8889548
9811942
10349636
10922068
11042159
11076861
11217851
12466851
12477932
12520002
12904583
12930873
14971039
15489334
15747579
15782199
15893969
16141072
16141073
16896013
18973680
19252486
19622788
20074551
20550962
21267068
22130515
22796066
22935416
23326410
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0045454  cell redox homeostasis
GO:0006662  glycerol ether metabolic process
GO:0055114  oxidation reduction

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005788  endoplasmic reticulum lumen

Molecular Function

GO:0009055  electron carrier activity
GO:0016853  isomerase activity
GO:0015035  protein disulfide oxidoreductase activity