NCK associated protein 1 like

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Synonym

NCK associated protein 1 like, 4930568P13Rik, Nckap1l, Hemp1, AI463083

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:- brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:7.60 artery/aorta:- vein:- lymphnode:64.80 peripheral blood:258.80 spleen:105.30 thymus:227.20 bone marrow:76.90 adipose:- bone:112.70 skin:7.90
GeneChip cerebrum:6.18 cerebellum:5.54 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.30 spine:6.20 retina:5.74 eye:6.65 artery/aorta:- vein:6.90 lymphnode:10.15 peripheral blood:- spleen:10.25 thymus:- bone marrow:9.72 adipose:6.77 bone:9.53 skin:6.15
CAGE cerebrum:1.31 cerebellum:- brain stem:1.49 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.21 retina:- eye:- artery/aorta:2.83 vein:- lymphnode:5.10 peripheral blood:- spleen:4.16 thymus:4.28 bone marrow:- adipose:- bone:4.22 skin:1.89
RNA-seq cerebrum:1.14 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:46 testis:73.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:45.30        lung:20.10    bladder:- kidney:16.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:62 salivary:54
GeneChip uterus:7.20 placenta:7.01 prostate:5.89 ovary:6.45 testis:7.82 heart:6.53 muscle:6.18 esophagus:- stomach:6.03 intestine:6.30 colon:- liver/hepato:6.36 lung:7.35 bladder:6.44 kidney:6.09 pituitary:6.77 thyroid/parathyroid:- adrenal gland:6.32 pancreas:6.23 breast:7.11 salivary:6.93
CAGE uterus:2.30 placenta:1.47 prostate:1.02 ovary:2.06 testis:4.59 heart:- muscle:- esophagus:- stomach:1.91 intestine:1.29 colon:2.32     liver/hepato:2.16    lung:3.43 bladder:2.31 kidney:- pituitary:1.75 thyroid/parathyroid:- adrenal gland:2.90 pancreas:2.83 breast:2.69 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.74 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.17        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_153505
Gene ID 105855
Unigene ID Mm.30805
Probe set ID 1428786_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022488

Orthologous Gene

Human[1]  NM_001184976, NM_005337
Rat[1]  NM_001108119, NM_005337

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11125038
11217851
11544199
12466851
12477932
16141072
16141073
18287559
19015308
20697350
21267068
21677750
22922362
23424621

Gene Ontology  (GO ID)

Biological Process

GO:0070358  actin polymerization-dependent cell motility
GO:0001782  B cell homeostasis
GO:0050853  B cell receptor signaling pathway
GO:0030866  cortical actin cytoskeleton organization
GO:0030011  maintenance of cell polarity
GO:0002262  myeloid cell homeostasis
GO:0043066  negative regulation of apoptosis
GO:0032700  negative regulation of interleukin-17 production
GO:0032715  negative regulation of interleukin-6 production
GO:0030593  neutrophil chemotaxis
GO:0030838  positive regulation of actin filament polymerization
GO:0045579  positive regulation of B cell differentiation
GO:0030890  positive regulation of B cell proliferation
GO:0043372  positive regulation of CD4-positive, alpha beta T cell differentiation
GO:0043378  positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0033630  positive regulation of cell adhesion mediated by integrin
GO:0045648  positive regulation of erythrocyte differentiation
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0045621  positive regulation of lymphocyte differentiation
GO:0090023  positive regulation of neutrophil chemotaxis
GO:0060100  positive regulation of phagocytosis, engulfment
GO:0042327  positive regulation of phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0032855  positive regulation of Rac GTPase activity
GO:0042102  positive regulation of T cell proliferation
GO:0006461  protein complex assembly
GO:0042221  response to chemical stimulus
GO:0042493  response to drug
GO:0043029  T cell homeostasis

Cellular Component

GO:0005829  cytosol
GO:0031209  SCAR complex

Molecular Function

GO:0032403  protein complex binding
GO:0030295  protein kinase activator activity
GO:0030675  Rac GTPase activator activity