myosin, light polypeptide kinase

Synonym

myosin, light polypeptide kinase, MLCK210, MLCK108, A930019C19Rik, AW489456, Mylk, KRP, Myosin light chain kinase, smooth muscle, 9530072E15Rik, Kinase-related protein, MLCK, telokin, Mlck, Telokin

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:6.65

cerebellum:6.46

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.73

spine:6.91

retina:6.84

eye:7.82

artery/aorta:-

vein:12.49

lymphnode:7.94

peripheral blood:-

spleen:9.12

thymus:-

bone marrow:8.21

adipose:9.11

bone:8.51

skin:9.32

CAGE

cerebrum:1.78

cerebellum:-

brain stem:2.52

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.17

retina:-

eye:-

artery/aorta:4.56

vein:-

lymphnode:3.52

peripheral blood:-

spleen:2.88

thymus:1.43

bone marrow:-

adipose:-

bone:2.66

skin:3.64

RNA-seq

cerebrum:1.97

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:12.99

placenta:8.32

prostate:11.10

ovary:11.86

testis:8.49

heart:9.06

muscle:8.85

esophagus:-

stomach:12.22

intestine:12.34

colon:-

liver/hepato:8.77

lung:11.14

bladder:13.92

kidney:9.63

pituitary:6.80

thyroid/parathyroid:-

adrenal gland:8.91

pancreas:6.79

breast:10.09

salivary:9.35

CAGE

uterus:6.34

placenta:3.05

prostate:5.74

ovary:5.87

testis:3.75

heart:-

muscle:-

esophagus:-

stomach:6.14

intestine:5.62

colon:5.52

liver/hepato:2.76

lung:4.52

bladder:7.93

kidney:-

pituitary:2.22

thyroid/parathyroid:-

adrenal gland:3.24

pancreas:2.33

breast:5.11

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.42

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:4.45

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_139300
Gene ID	107589
Unigene ID	-
Probe set ID	1425505_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022836

Orthologous Gene

Human[5]	NM_053025, NM_053026, NM_053027, NM_053031, NM_053032
Rat[1]	NM_001105874, NM_053026, NM_053027, NM_053031, NM_053032

Chromosomal Region

Gene Family (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0060414	aorta smooth muscle tissue morphogenesis
GO:0032060	bleb formation
GO:0071476	cellular hypotonic response
GO:0016310	phosphorylation
GO:0051928	positive regulation of calcium ion transport
GO:0030335	positive regulation of cell migration
GO:0006468	protein amino acid phosphorylation
GO:0006939	smooth muscle contraction
GO:0014820	tonic smooth muscle contraction

Cellular Component

GO:0042995	cell projection
GO:0032154	cleavage furrow
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0030027	lamellipodium
GO:0005886	plasma membrane
GO:0001725	stress fiber

Molecular Function

GO:0003779	actin binding
GO:0005524	ATP binding
GO:0005516	calmodulin binding
GO:0019899	enzyme binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0004687	myosin light chain kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

myosin, light polypeptide kinase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function