coiled coil domain containing 88A

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Synonym

Ape, C130096N06Rik, RIKEN cDNA A430106J12 gene, A430106J12Rik, Hkrp1, Giv, C330012F17Rik, AI848406, D130005J21Rik, GIV

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.70 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:32.10 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:9.90 bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.69 cerebellum:7.94 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.64 spine:8.53 retina:7.91 eye:6.36 artery/aorta:- vein:7.54 lymphnode:8.15 peripheral blood:- spleen:7.59 thymus:- bone marrow:7.44 adipose:5.82 bone:7.75 skin:6.06
CAGE cerebrum:3.23 cerebellum:- brain stem:3.34 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.63 retina:- eye:- artery/aorta:2.61 vein:- lymphnode:2.99 peripheral blood:- spleen:2.65 thymus:2.61 bone marrow:- adipose:- bone:3.18 skin:2.54
RNA-seq cerebrum:1.03 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:71 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:424.40 pancreas:- breast:- salivary:-
GeneChip uterus:7.33 placenta:5.48 prostate:5.18 ovary:7.40 testis:7.28 heart:5.42 muscle:5.24 esophagus:- stomach:5.16 intestine:5 colon:- liver/hepato:3.75 lung:6.49 bladder:6.80 kidney:4.57 pituitary:7.45 thyroid/parathyroid:- adrenal gland:7.17 pancreas:4.38 breast:6.29 salivary:4.63
CAGE uterus:2.73 placenta:2.08 prostate:1.41 ovary:3.01 testis:4.75 heart:- muscle:- esophagus:- stomach:0 intestine:1.05 colon:1.19     liver/hepato:0.64    lung:2.65 bladder:2.25 kidney:- pituitary:3.23 thyroid/parathyroid:- adrenal gland:2.64 pancreas:0.84 breast:1.78 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.32 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0.68        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_176841
Gene ID 108686
Unigene ID Mm.441367
Probe set ID 1437216_at  [Mouse430_2]
Ensembl ID ENSMUSG00000032740

Orthologous Gene

Human[4]  NM_001135597, NM_018084
Rat[4]  NM_001135597, NM_018084

Chromosomal Region

11A3.3  [29,273,658  -  29,410,812]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
12466851
12477932
12520002
12904583
14621295
15749703
15753085
15882442
16141072
16141073
16944949
16959763
18264090
18316593
19778506
19778507
20157114
21267068
21415395
21632933
22574214
22974978
23195430
23886629

Gene Ontology  (GO ID)

Biological Process

GO:0032148  activation of protein kinase B activity
GO:0016477  cell migration
GO:0006260  DNA replication
GO:0030032  lamellipodium assembly
GO:0016044  membrane organization
GO:0007399  nervous system development
GO:0032956  regulation of actin cytoskeleton organization
GO:0042127  regulation of cell proliferation
GO:0006275  regulation of DNA replication
GO:0010975  regulation of neuron projection development
GO:0001932  regulation of protein amino acid phosphorylation
GO:0031929  TOR signaling pathway

Cellular Component

GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005794  Golgi apparatus
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0003779  actin binding
GO:0008017  microtubule binding
GO:0035091  phosphoinositide binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0043422  protein kinase B binding