farnesyltransferase, CAAX box, beta

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Synonym

2010013E13Rik, FTase-beta, Fntb, AA409500, farnesyltransferase, CAAX box, beta, CAAX farnesyltransferase subunit beta, Protein farnesyltransferase subunit beta, RAS proteins prenyltransferase beta

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:29.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:257.80 peripheral nerve:57.30 spine:141.90 retina:128.60 eye:15.20 artery/aorta:- vein:- lymphnode:108 peripheral blood:- spleen:223.80 thymus:59.30 bone marrow:- adipose:- bone:12.50 skin:31.70
GeneChip cerebrum:7.59 cerebellum:7.98 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.30 spine:9.01 retina:7.26 eye:7.13 artery/aorta:- vein:7.41 lymphnode:7.08 peripheral blood:- spleen:7.45 thymus:- bone marrow:8.40 adipose:7.17 bone:7.41 skin:7.22
CAGE cerebrum:1.36 cerebellum:- brain stem:1.83 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.77 retina:- eye:- artery/aorta:0.89 vein:- lymphnode:0.83 peripheral blood:- spleen:0.29 thymus:0.27 bone marrow:- adipose:- bone:0 skin:0.15
RNA-seq cerebrum:7.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:218.10 placenta:41.40 prostate:- ovary:- testis:22.20 heart:37.20 muscle:106.50 esophagus:- stomach:- intestine:73.90 colon:17.60     liver/hepato:36.20        lung:80.30    bladder:- kidney:8.10 pituitary:- thyroid/parathyroid:112.50 adrenal gland:- pancreas:- breast:49 salivary:54
GeneChip uterus:7.82 placenta:8.93 prostate:7.53 ovary:7.31 testis:6.91 heart:7.38 muscle:7.55 esophagus:- stomach:7.31 intestine:7.67 colon:- liver/hepato:6.62 lung:7.18 bladder:7.06 kidney:6.84 pituitary:8.41 thyroid/parathyroid:- adrenal gland:7.09 pancreas:6.67 breast:7.20 salivary:7.55
CAGE uterus:0.83 placenta:1.64 prostate:0.37 ovary:0.62 testis:0.75 heart:- muscle:- esophagus:- stomach:0.67 intestine:0.58 colon:0     liver/hepato:0.26    lung:0.75 bladder:0.93 kidney:- pituitary:1.56 thyroid/parathyroid:- adrenal gland:1.12 pancreas:0 breast:0.75 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.12 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.73        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_145927
Gene ID 110606
Unigene ID Mm.151174
Probe set ID 1434309_at  [Mouse430_2]
Ensembl ID ENSMUSG00000033373

Orthologous Gene

Human[2]  NM_002028
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
10842103
10922068
11042159
11076861
11217851
12466851
12477932
12904583
14610273
15489334
15782199
15837621
16141072
16141073
17967808
18799693
19093225
19723774
20106865
20308544
21266780
21267068
22039581
23686339
24136196

Gene Ontology  (GO ID)

Biological Process

GO:0008152  metabolic process
GO:0008285  negative regulation of cell proliferation
GO:0045787  positive regulation of cell cycle
GO:0008284  positive regulation of cell proliferation
GO:0048146  positive regulation of fibroblast proliferation
GO:0051770  positive regulation of nitric-oxide synthase biosynthetic process
GO:0018343  protein farnesylation
GO:0042127  regulation of cell proliferation
GO:0034097  response to cytokine stimulus
GO:0010035  response to inorganic substance
GO:0014070  response to organic cyclic substance
GO:0042060  wound healing

Cellular Component

GO:0005875  microtubule associated complex
GO:0043234  protein complex
GO:0005965  protein farnesyltransferase complex

Molecular Function

GO:0003824  catalytic activity
GO:0008144  drug binding
GO:0004311  farnesyltranstransferase activity
GO:0019840  isoprenoid binding
GO:0046872  metal ion binding
GO:0042277  peptide binding
GO:0004659  prenyltransferase activity
GO:0004660  protein farnesyltransferase activity
GO:0016740  transferase activity
GO:0008270  zinc ion binding