nephronectin

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Synonym

1110009H02Rik, nephronectin, Npnt, AI314031, POEM, AA682063, Nctn

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:17.40 cerebellum:18.40 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:- retina:- eye:60.80 artery/aorta:337.60 vein:- lymphnode:- peripheral blood:- spleen:13.20 thymus:- bone marrow:- adipose:- bone:12.50 skin:7.90
GeneChip cerebrum:6.08 cerebellum:5.33 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.87 spine:5.01 retina:6.44 eye:8.66 artery/aorta:- vein:8.59 lymphnode:4.82 peripheral blood:- spleen:9.62 thymus:- bone marrow:5.08 adipose:6.66 bone:6.03 skin:8.08
CAGE cerebrum:1.58 cerebellum:- brain stem:1.10 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.83 retina:- eye:- artery/aorta:5.01 vein:- lymphnode:0.57 peripheral blood:- spleen:3.26 thymus:1.69 bone marrow:- adipose:- bone:1.51 skin:2.69
RNA-seq cerebrum:1.95 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:- prostate:- ovary:23 testis:- heart:37.20 muscle:106.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:110.50    bladder:- kidney:169.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:18.80 breast:39.20 salivary:-
GeneChip uterus:8.79 placenta:7.13 prostate:6.17 ovary:7.88 testis:4.93 heart:5.73 muscle:7.86 esophagus:- stomach:7.89 intestine:7.05 colon:- liver/hepato:5.20 lung:12.47 bladder:5.66 kidney:10.40 pituitary:6.11 thyroid/parathyroid:- adrenal gland:7.05 pancreas:4.67 breast:7.07 salivary:5.02
CAGE uterus:2.95 placenta:1.71 prostate:1.51 ovary:2.94 testis:0.45 heart:- muscle:- esophagus:- stomach:2.95 intestine:3.06 colon:3.21     liver/hepato:0    lung:5.80 bladder:1.08 kidney:- pituitary:1.63 thyroid/parathyroid:- adrenal gland:2.42 pancreas:0 breast:2.36 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.55 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0.94        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_033525
Gene ID 114249
Unigene ID Mm.279310
Probe set ID 1452106_at  [Mouse430_2]
Ensembl ID ENSMUSG00000040998

Orthologous Gene

Human[1]  NM_001033047, NM_001184690, NM_001184691, NM_001184692, NM_001184693
Rat[1]  NM_001033047, NM_001184690, NM_001184691, NM_001184692, NM_001184693

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

10349636
10922068
11042159
11076861
11217851
11470831
11544199
11546798
12466851
12477932
12682087
14610273
14681479
15782199
16141072
16141073
16829211
17328885
17537792
18271919
18287559
18757743
19342381
19449303
19844573
19944102
20439720
20452350
20562862
21267068
21335239
21440680
21491542
21689636
21784074
21903675
21924257
22613833
22696295
22842459
23206711
23271346
23357641
23920117

Gene Ontology  (GO ID)

Biological Process

GO:0001658  branching involved in ureteric bud morphogenesis
GO:0007155  cell adhesion
GO:0030154  cell differentiation
GO:0033631  cell-cell adhesion mediated by integrin
GO:0007160  cell-matrix adhesion
GO:0071356  cellular response to tumor necrosis factor
GO:0045184  establishment of protein localization
GO:0030198  extracellular matrix organization
GO:0007275  multicellular organismal development
GO:0010694  positive regulation of alkaline phosphatase activity
GO:0010811  positive regulation of cell-substrate adhesion
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0045669  positive regulation of osteoblast differentiation
GO:0045987  positive regulation of smooth muscle contraction
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0001657  ureteric bud development

Cellular Component

GO:0034678  alpha8-beta1 integrin complex
GO:0005604  basement membrane
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0016020  membrane
GO:0005578  proteinaceous extracellular matrix
GO:0030485  smooth muscle contractile fiber

Molecular Function

GO:0005509  calcium ion binding
GO:0005178  integrin binding