adenosine A2b receptor

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Synonym

adenosine A2b receptor, Adora2b, AI480866, MGC144574, Adenosine A2b receptor, AI605384, MGC144575

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:12.20

cerebellum:110.50

brain stem:158.90

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:236.40

retina:96.40

eye:7.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:89.80

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.99

cerebellum:4.86

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.09

spine:5.99

retina:5.81

eye:5.27

artery/aorta:-

vein:5.91

lymphnode:4.75

peripheral blood:-

spleen:4.83

thymus:-

bone marrow:5.35

adipose:4.92

bone:5.13

skin:6.30

CAGE

cerebrum:1.40

cerebellum:-

brain stem:2.00

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.53

retina:-

eye:-

artery/aorta:1.06

vein:-

lymphnode:1.41

peripheral blood:-

spleen:1.27

thymus:0.49

bone marrow:-

adipose:-

bone:0.63

skin:3.04

RNA-seq

cerebrum:1.03

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:13.80

prostate:-

ovary:11.50

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:52.90

liver/hepato:-

lung:40.20

bladder:132.40

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.78

placenta:6.11

prostate:5.06

ovary:4.71

testis:5.31

heart:4.99

muscle:4.77

esophagus:-

stomach:5.03

intestine:4.91

colon:-

liver/hepato:5.21

lung:6.27

bladder:6.87

kidney:5.01

pituitary:4.76

thyroid/parathyroid:-

adrenal gland:4.49

pancreas:5.59

breast:4.86

salivary:5.07

CAGE

uterus:1.10

placenta:2.68

prostate:1.02

ovary:1.14

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:2.49

colon:2.66

liver/hepato:0

lung:2.57

bladder:3.46

kidney:-

pituitary:0.52

thyroid/parathyroid:-

adrenal gland:0.37

pancreas:0.84

breast:0.58

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:0.46

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007413
Gene ID	11541
Unigene ID	Mm.40740
Probe set ID	1450214_at [Mouse430_2]
Ensembl ID	ENSMUSG00000018500

Orthologous Gene

Human[1]	NM_000676
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR001435	Adenosine A2B receptor
IPR001634	Adenosine receptor
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0001973	adenosine receptor signaling pathway
GO:0031668	cellular response to extracellular stimulus
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0008285	negative regulation of cell proliferation
GO:0032966	negative regulation of collagen biosynthetic process
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0033605	positive regulation of catecholamine secretion
GO:0008284	positive regulation of cell proliferation
GO:0030828	positive regulation of cGMP biosynthetic process
GO:0032722	positive regulation of chemokine production
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus
GO:0031284	positive regulation of guanylate cyclase activity
GO:0032755	positive regulation of interleukin-6 production
GO:0043306	positive regulation of mast cell degranulation
GO:0010701	positive regulation of norepinephrine secretion
GO:0010893	positive regulation of steroid biosynthetic process
GO:0045909	positive regulation of vasodilation
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0045765	regulation of angiogenesis
GO:0060087	relaxation of vascular smooth muscle
GO:0007165	signal transduction

Cellular Component

GO:0009986	cell surface
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0001609	adenosine receptor activity, G-protein coupled
GO:0004930	G-protein coupled receptor activity
GO:0004871	signal transducer activity

adenosine A2b receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function