angiogenin, ribonuclease, RNase A family, 5

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Synonym

RNase 5, Rnase5a, angiogenin, ribonuclease A family, member 1, Angiogenin-1 precursor, AI385586, Ribonuclease 5, Ang, Ang1, Rnase5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:6.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:257.80 peripheral nerve:19.10 spine:- retina:- eye:15.20 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:- spleen:- thymus:29.60 bone marrow:- adipose:- bone:62.60 skin:23.80
GeneChip cerebrum:3.96 cerebellum:3.68 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.92 spine:4.03 retina:3.81 eye:4.02 artery/aorta:- vein:5.55 lymphnode:3.88 peripheral blood:- spleen:3.89 thymus:- bone marrow:4.19 adipose:4.70 bone:4.22 skin:5.52
CAGE nodata
RNA-seq cerebrum:8.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:55.20 prostate:123.50 ovary:- testis:7.40 heart:74.40 muscle:319.60 esophagus:- stomach:- intestine:- colon:88.10     liver/hepato:787.40        lung:70.30    bladder:- kidney:48.40 pituitary:- thyroid/parathyroid:112.50 adrenal gland:- pancreas:328.40 breast:55.50 salivary:54
GeneChip uterus:6.59 placenta:5.07 prostate:4.15 ovary:5.15 testis:3.96 heart:4.49 muscle:4.24 esophagus:- stomach:6.70 intestine:7.04 colon:- liver/hepato:10.24 lung:7.89 bladder:5.99 kidney:4.01 pituitary:3.93 thyroid/parathyroid:- adrenal gland:4.20 pancreas:7.67 breast:4.35 salivary:4.26
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:67.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007447
Gene ID 11727
Unigene ID Mm.202665
Probe set ID 1450717_at  [Mouse430_2]
Ensembl ID ENSMUSG00000072115

Orthologous Gene

Human[1]  NM_001097577, NM_001145
Rat [0]  

Chromosomal Region

14C1  [51,710,752  -  51,721,682]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1346389
2222458
8275705
8288233
8448182
8530072
8833241
8889548
9325265
10349636
10737774
11042159
11076861
11217851
11437607
12466851
12477932
12548285
14749497
15016731
15073150
15107403
15184386
15489334
15613470
15637314
15676279
15722482
15882861
16107612
16141072
16141073
16301790
16514057
16969722
17468498
17486412
17573777
18936943
19028450
19109488
19114040
19258415
19276260
19332886
19444281
19644017
20060382
20133818
20692235
20739392
21267068
21550017
22234465
22406061
22496549
23576605

Gene Ontology  (GO ID)

Biological Process

GO:0032431  activation of phospholipase A2 activity
GO:0007202  activation of phospholipase C activity
GO:0032148  activation of protein kinase B activity
GO:0001525  angiogenesis
GO:0030154  cell differentiation
GO:0016477  cell migration
GO:0007417  central nervous system development
GO:0006651  diacylglycerol biosynthetic process
GO:0007275  multicellular organismal development
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0017148  negative regulation of translation
GO:0001938  positive regulation of endothelial cell proliferation
GO:0042327  positive regulation of phosphorylation
GO:0050714  positive regulation of protein secretion
GO:0009725  response to hormone stimulus
GO:0001666  response to hypoxia
GO:0006950  response to stress
GO:0009303  rRNA transcription

Cellular Component

GO:0032311  angiogenin-PRI complex
GO:0005605  basal lamina
GO:0005604  basement membrane
GO:0043025  cell soma
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0030426  growth cone
GO:0005634  nucleus
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0003779  actin binding
GO:0005507  copper ion binding
GO:0003677  DNA binding
GO:0004519  endonuclease activity
GO:0008201  heparin binding
GO:0016787  hydrolase activity
GO:0004518  nuclease activity
GO:0003676  nucleic acid binding
GO:0004522  pancreatic ribonuclease activity
GO:0042277  peptide binding
GO:0005102  receptor binding
GO:0004540  ribonuclease activity
GO:0003723  RNA binding