apolipoprotein C-III

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Synonym

Apolipoprotein C-III precursor, apolipoprotein C-III, ApoC-III, Apo-CIII, Apoc, Apoc3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.11 cerebellum:4.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4 spine:4.41 retina:4.41 eye:4.31 artery/aorta:- vein:3.83 lymphnode:4.07 peripheral blood:- spleen:4.15 thymus:- bone marrow:4.28 adipose:5.70 bone:4.10 skin:4.19
CAGE cerebrum:0.10 cerebellum:- brain stem:0.32 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:2.33 vein:- lymphnode:0 peripheral blood:- spleen:0.71 thymus:1.06 bone marrow:- adipose:- bone:0.63 skin:0.29
RNA-seq cerebrum:25.61 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:71 esophagus:- stomach:65.50 intestine:147.90 colon:704.90     liver/hepato:914.10        lung:-    bladder:- kidney:16.10 pituitary:25.80 thyroid/parathyroid:- adrenal gland:- pancreas:9.40 breast:- salivary:-
GeneChip uterus:4.48 placenta:5.47 prostate:4.01 ovary:4.75 testis:4.19 heart:4.95 muscle:5.45 esophagus:- stomach:4.74 intestine:7.55 colon:- liver/hepato:14.08 lung:9.02 bladder:4.49 kidney:7.32 pituitary:4.96 thyroid/parathyroid:- adrenal gland:6.80 pancreas:4.75 breast:5.34 salivary:4.09
CAGE uterus:0 placenta:1.67 prostate:0 ovary:1.05 testis:0 heart:- muscle:- esophagus:- stomach:3.29 intestine:7.81 colon:7.51     liver/hepato:9.44    lung:0 bladder:0.77 kidney:- pituitary:0.99 thyroid/parathyroid:- adrenal gland:3.54 pancreas:0 breast:1.04 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.45 esophagus:- stomach:- intestine:- colon:-     liver/hepato:896.07        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_023114
Gene ID 11814
Unigene ID Mm.390161
Probe set ID 1418278_at  [Mouse430_2]
Ensembl ID ENSMUSG00000032081

Orthologous Gene

Human[1]  NM_000040
Rat[1]  NM_000040

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1450516
1478650
6099394
7035547
7868970
8089130
8689583
8864964
8994037
9616220
9873036
10073946
10349636
11002334
11042159
11076861
11217851
11478940
11551841
11557675
11590213
11814582
11959336
11983814
12466851
12477932
12810823
14610273
14974682
14983036
15117734
15489334
15649902
15734841
15863838
16141072
16141073
16461842
16478678
16497661
16498401
17916774
18243209
18263930
18678879
18722179
19121312
19542564
20889132
21183731
21793029
23949443
24449835

Gene Ontology  (GO ID)

Biological Process

GO:0033344  cholesterol efflux
GO:0042632  cholesterol homeostasis
GO:0008203  cholesterol metabolic process
GO:0034382  chylomicron remnant clearance
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0034375  high-density lipoprotein particle remodeling
GO:0016042  lipid catabolic process
GO:0006629  lipid metabolic process
GO:0006869  lipid transport
GO:0042157  lipoprotein metabolic process
GO:0060621  negative regulation of cholesterol import
GO:0045717  negative regulation of fatty acid biosynthetic process
GO:0010987  negative regulation of high-density lipoprotein particle clearance
GO:0050995  negative regulation of lipid catabolic process
GO:0045833  negative regulation of lipid metabolic process
GO:0051005  negative regulation of lipoprotein lipase activity
GO:0010989  negative regulation of low-density lipoprotein particle clearance
GO:0048261  negative regulation of receptor-mediated endocytosis
GO:0010897  negative regulation of triglyceride catabolic process
GO:0010916  negative regulation of very-low-density lipoprotein particle clearance
GO:0010903  negative regulation of very-low-density lipoprotein particle remodeling
GO:0033700  phospholipid efflux
GO:0032489  regulation of Cdc42 protein signal transduction
GO:0006810  transport
GO:0019433  triglyceride catabolic process
GO:0070328  triglyceride homeostasis
GO:0006641  triglyceride metabolic process
GO:0006642  triglyceride mobilization

Cellular Component

GO:0042627  chylomicron
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0034363  intermediate-density lipoprotein particle
GO:0034366  spherical high-density lipoprotein particle
GO:0034361  very-low-density lipoprotein particle

Molecular Function

GO:0030234  enzyme regulator activity
GO:0070653  high-density lipoprotein receptor binding
GO:0055102  lipase inhibitor activity
GO:0008289  lipid binding
GO:0005543  phospholipid binding