aquaporin 1

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Synonym

Aqp1, Aquaporin-CHIP, Early response protein DER2, aquaporin 1, AQP-1, Aquaporin-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.80 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:773.40 peripheral nerve:2656.10 spine:47.30 retina:32.10 eye:136.80 artery/aorta:337.60 vein:- lymphnode:43.20 peripheral blood:359.40 spleen:1079.60 thymus:69.20 bone marrow:25.60 adipose:212.70 bone:425.80 skin:158.40
GeneChip cerebrum:5.44 cerebellum:6.87 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.27 spine:5.28 retina:8.30 eye:8.98 artery/aorta:- vein:8.87 lymphnode:10.28 peripheral blood:- spleen:9.44 thymus:- bone marrow:12.93 adipose:11.29 bone:12.44 skin:10.43
CAGE cerebrum:1.38 cerebellum:- brain stem:0.47 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.32 retina:- eye:- artery/aorta:4.44 vein:- lymphnode:2.94 peripheral blood:- spleen:5.52 thymus:2.32 bone marrow:- adipose:- bone:5.53 skin:3.23
RNA-seq cerebrum:11.69 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:23 testis:- heart:223.20 muscle:177.50 esophagus:- stomach:32.70 intestine:258.80 colon:141     liver/hepato:72.40        lung:271.10    bladder:397.10 kidney:733.40 pituitary:51.70 thyroid/parathyroid:224.90 adrenal gland:- pancreas:28.10 breast:97.90 salivary:108
GeneChip uterus:11.05 placenta:10.20 prostate:9.15 ovary:9.98 testis:4.69 heart:11.65 muscle:11.69 esophagus:- stomach:8.49 intestine:10.10 colon:- liver/hepato:10.28 lung:12.57 bladder:11.67 kidney:12.66 pituitary:5.51 thyroid/parathyroid:- adrenal gland:10.02 pancreas:8.69 breast:11.05 salivary:7.23
CAGE uterus:3.56 placenta:4.33 prostate:2.59 ovary:3.45 testis:0 heart:- muscle:- esophagus:- stomach:2.52 intestine:3.99 colon:4.36     liver/hepato:4.36    lung:5.49 bladder:4.66 kidney:- pituitary:0.29 thyroid/parathyroid:- adrenal gland:3.30 pancreas:2.90 breast:4.25 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:34.15 esophagus:- stomach:- intestine:- colon:-     liver/hepato:14.26        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007472
Gene ID 11826
Unigene ID Mm.18625
Probe set ID 1416203_at  [Mouse430_2]
Ensembl ID ENSMUSG00000004655

Orthologous Gene

Human[2]  NM_001185060, NM_001185061, NM_001185062, NM_198098
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR012269  Aquaporin
IPR000425  Major intrinsic protein

Link to Pubmed  (Pubmed ID)

1508193
8586439
8703970
9374641
9468475
9507200
9689137
9757370
9822113
9886922
10021457
10021464
10191100
10232700
10349636
10400615
10613915
10642600
10644730
10662735
10698922
10724035
10788316
10795927
10836992
10839360
10856128
10870513
11035042
11042159
11066060
11076861
11078688
11121384
11217851
11226337
11382807
11406631
11415940
11698654
11741725
11891232
11954676
12031518
12034763
12083525
12096051
12133842
12181190
12466851
12477932
12565800
12600999
12676067
12759225
12943377
14637313
14675051
14753499
15003543
15283758
15489334
15496149
15507545
15557451
15632069
15647343
15647389
15713911
15815633
15838507
15844003
15859952
15952169
15998844
16039047
16079275
16133142
16141072
16141073
16319116
16427635
16472605
16476579
16508653
16508658
16525162
16571784
16574458
16582023
16602821
16624821
16871401
16936111
17195181
17251353
17257750
17377981
17633275
17728008
17868659
17898307
17913837
17941896
17943079
17965968
18172001
18231833
18287559
18296079
18353863
18434389
18511498
18554416
18600340
18618131
18665841
18806227
19136711
19179619
19215235
19291583
19298815
19367412
19570847
19584911
19628672
19668215
19724054
19774080
19855135
20018876
20029450
20121927
20231275
20235219
20383338
20530543
20639513
20668095
20853510
20938728
20957496
20978075
21040788
21147077
21181199
21267068
21269951
21347258
21451971
21511033
21519870
21677750
21705333
21735643
21854740
21859894
21925491
21947380
22043022
22076439
22174795
22226856
22237799
22323586
22357733
22491945
22674028
22820194
23029502
23087172
23177919
23238222
23243273
23341629
23948641
24049145
24058167
24334548

Gene Ontology  (GO ID)

Biological Process

GO:0051458  adrenocorticotropin secretion
GO:0015696  ammonium transport
GO:0048593  camera-type eye morphogenesis
GO:0015670  carbon dioxide transport
GO:0006884  cell volume homeostasis
GO:0019725  cellular homeostasis
GO:0071474  cellular hyperosmotic response
GO:0071320  cellular response to cAMP
GO:0071280  cellular response to copper ion
GO:0070301  cellular response to hydrogen peroxide
GO:0071456  cellular response to hypoxia
GO:0071241  cellular response to inorganic substance
GO:0071260  cellular response to mechanical stimulus
GO:0071288  cellular response to mercury ion
GO:0071300  cellular response to retinoic acid
GO:0071472  cellular response to salt stress
GO:0033554  cellular response to stress
GO:0034644  cellular response to UV
GO:0006182  cGMP biosynthetic process
GO:0030950  establishment or maintenance of actin cytoskeleton polarity
GO:0003094  glomerular filtration
GO:0015793  glycerol transport
GO:0044241  lipid digestion
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0030185  nitric oxide transport
GO:0045766  positive regulation of angiogenesis
GO:0030335  positive regulation of cell migration
GO:0010634  positive regulation of epithelial cell migration
GO:0048146  positive regulation of fibroblast proliferation
GO:0010592  positive regulation of lamellipodium assembly
GO:0046878  positive regulation of saliva secretion
GO:0006813  potassium ion transport
GO:0070295  renal water absorption
GO:0003097  renal water transport
GO:0042493  response to drug
GO:0032940  secretion by cell
GO:0033363  secretory granule organization
GO:0019233  sensory perception of pain
GO:0055085  transmembrane transport
GO:0006810  transport
GO:0030104  water homeostasis
GO:0006833  water transport
GO:0042060  wound healing

Cellular Component

GO:0045177  apical part of cell
GO:0016324  apical plasma membrane
GO:0030424  axon
GO:0009925  basal plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005903  brush border
GO:0031526  brush border membrane
GO:0032809  cell soma membrane
GO:0005737  cytoplasm
GO:0032127  dense core granule membrane
GO:0070062  extracellular vesicular exosome
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0043679  nerve terminal
GO:0043005  neuron projection
GO:0031965  nuclear membrane
GO:0005634  nucleus
GO:0020005  parasitophorous vacuolar membrane
GO:0020003  parasitophorous vacuole
GO:0005886  plasma membrane
GO:0042383  sarcolemma

Molecular Function

GO:0051739  ammonia transporter activity
GO:0046875  ephrin receptor binding
GO:0015168  glycerol transmembrane transporter activity
GO:0005223  intracellular cGMP activated cation channel activity
GO:0030184  nitric oxide transporter activity
GO:0005267  potassium channel activity
GO:0015079  potassium ion transmembrane transporter activity
GO:0022857  transmembrane transporter activity
GO:0005215  transporter activity
GO:0015250  water channel activity
GO:0005372  water transporter activity