ATPase, Na+/K+ transporting, alpha 1 polypeptide

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Synonym

Na+/K+ ATPase 1, Sodium pump 1, Atpa-1, MGC38419, BC010319, ATPase, Na+/K+ transporting, alpha 1 polypeptide, Atp1a1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:331.70

cerebellum:165.80

brain stem:63.60

corpus callosum/glia:-

pineal gland:-

peripheral nerve:764.30

spine:141.90

retina:160.70

eye:349.50

artery/aorta:84.40

vein:-

lymphnode:10.80

peripheral blood:129.40

spleen:92.20

thymus:148.20

bone marrow:577

adipose:-

bone:413.30

skin:443.40

GeneChip

cerebrum:10.37

cerebellum:11.41

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:12.27

spine:10.19

retina:7.90

eye:8.32

artery/aorta:-

vein:8.79

lymphnode:8.61

peripheral blood:-

spleen:9.71

thymus:-

bone marrow:8.80

adipose:8.62

bone:9.16

skin:8.59

CAGE

cerebrum:5.74

cerebellum:-

brain stem:4.75

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:5.24

retina:-

eye:-

artery/aorta:3.99

vein:-

lymphnode:4.05

peripheral blood:-

spleen:4.36

thymus:4.82

bone marrow:-

adipose:-

bone:4.26

skin:4.73

RNA-seq

cerebrum:149.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:345.20

prostate:-

ovary:160.90

testis:155.20

heart:576.60

muscle:106.50

esophagus:-

stomach:490.90

intestine:1035.20

colon:1251.20

liver/hepato:126.70

lung:823.40

bladder:132.40

kidney:1579.60

pituitary:361.70

thyroid/parathyroid:674.80

adrenal gland:-

pancreas:187.60

breast:1051.30

salivary:1403.90

GeneChip

uterus:11.04

placenta:10.50

prostate:10.71

ovary:10.73

testis:8.39

heart:11.01

muscle:8.96

esophagus:-

stomach:10.92

intestine:12.11

colon:-

liver/hepato:10.10

lung:10.63

bladder:9.92

kidney:13.12

pituitary:10.64

thyroid/parathyroid:-

adrenal gland:10.10

pancreas:8.94

breast:9.32

salivary:11.75

CAGE

uterus:5.87

placenta:5.33

prostate:5.15

ovary:5.31

testis:3.16

heart:-

muscle:-

esophagus:-

stomach:4.79

intestine:7.21

colon:7.17

liver/hepato:5.65

lung:5.36

bladder:5.30

kidney:-

pituitary:5.33

thyroid/parathyroid:-

adrenal gland:5.89

pancreas:4.89

breast:5.21

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:11.57

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:64.22

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_144900
Gene ID	11928
Unigene ID	Mm.280103
Probe set ID	1423653_at [Mouse430_2]
Ensembl ID	ENSMUSG00000033161

Orthologous Gene

Human[3]	NM_000701, NM_001160233, NM_001160234
Rat[3]	NM_000701, NM_001160233, NM_001160234

Chromosomal Region

Gene Family (Interpro ID)

IPR006069	ATPase, P-type cation exchange, alpha subunit
IPR005775	ATPase, P-type cation exchange, alpha subunit, eukaryotic
IPR001757	ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter

Gene Ontology (GO ID)

Biological Process

GO:0006754	ATP biosynthetic process
GO:0006200	ATP catabolic process
GO:0006812	cation transport
GO:0071260	cellular response to mechanical stimulus
GO:0016311	dephosphorylation
GO:0006811	ion transport
GO:0060081	membrane hyperpolarization
GO:0015672	monovalent inorganic cation transport
GO:0031947	negative regulation of glucocorticoid biosynthetic process
GO:0045822	negative regulation of heart contraction
GO:0045823	positive regulation of heart contraction
GO:0045989	positive regulation of striated muscle contraction
GO:0010107	potassium ion import
GO:0006813	potassium ion transport
GO:0008217	regulation of blood pressure
GO:0002028	regulation of sodium ion transport
GO:0002026	regulation of the force of heart contraction
GO:0042493	response to drug
GO:0006814	sodium ion transport
GO:0006810	transport

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0005901	caveola
GO:0005783	endoplasmic reticulum
GO:0005768	endosome
GO:0005794	Golgi apparatus
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005886	plasma membrane
GO:0042383	sarcolemma
GO:0005890	sodium:potassium-exchanging ATPase complex
GO:0030315	T-tubule

Molecular Function

GO:0003869	4-nitrophenylphosphatase activity
GO:0043531	ADP binding
GO:0030506	ankyrin binding
GO:0005524	ATP binding
GO:0019829	cation-transporting ATPase activity
GO:0051087	chaperone binding
GO:0016787	hydrolase activity
GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0046872	metal ion binding
GO:0015077	monovalent inorganic cation transmembrane transporter activity
GO:0000166	nucleotide binding
GO:0043548	phosphoinositide 3-kinase binding
GO:0030955	potassium ion binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0019901	protein kinase binding
GO:0031402	sodium ion binding
GO:0005391	sodium:potassium-exchanging ATPase activity

ATPase, Na+/K+ transporting, alpha 1 polypeptide

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function