ATPase, Ca++ transporting, plasma membrane 2

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Synonym

Atp2b2, dfw, wri, Pmca2, wms, Plasma membrane calcium pump isoform 2, Plasma membrane calcium-transporting ATPase 2, ATPase, Ca++ transporting, plasma membrane 2, D6Abb2e, PMCA2, Plasma membrane calcium ATPase isoform 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:267.40 cerebellum:442.10 brain stem:222.50 corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:236.40 retina:- eye:68.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:9.39 cerebellum:10.05 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.15 spine:9.11 retina:7.29 eye:5.25 artery/aorta:- vein:4.52 lymphnode:4.43 peripheral blood:- spleen:4.51 thymus:- bone marrow:4.53 adipose:4.71 bone:4.51 skin:4.57
CAGE cerebrum:5.52 cerebellum:- brain stem:5.19 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.29 retina:- eye:- artery/aorta:0.54 vein:- lymphnode:0 peripheral blood:- spleen:0.16 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq cerebrum:24.98 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:18.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:46.90 breast:35.90 salivary:-
GeneChip uterus:5.23 placenta:4.69 prostate:4.53 ovary:5.25 testis:5.68 heart:4.81 muscle:5.09 esophagus:- stomach:4.57 intestine:4.71 colon:- liver/hepato:4.33 lung:4.95 bladder:4.47 kidney:4.66 pituitary:6.58 thyroid/parathyroid:- adrenal gland:5.39 pancreas:6.21 breast:4.60 salivary:4.90
CAGE uterus:2.57 placenta:0.11 prostate:0.51 ovary:1.76 testis:0 heart:- muscle:- esophagus:- stomach:0.67 intestine:0.23 colon:0.41     liver/hepato:1.64    lung:0.83 bladder:0.68 kidney:- pituitary:3.59 thyroid/parathyroid:- adrenal gland:1.64 pancreas:0 breast:4.43 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.12 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.50        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_009723
Gene ID 11941
Unigene ID Mm.321755
Probe set ID 1420402_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030302

Orthologous Gene

Human[6]  NM_001001331, NM_001683
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR006069  ATPase, P-type cation exchange, alpha subunit
IPR006408  ATPase, P-type, calcium-transporting, PMCA-type
IPR001757  ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter

Link to Pubmed  (Pubmed ID)

1974816
2765934
3038581
7518067
7537672
7587388
7587399
7683393
7948855
8530061
8858346
9325047
9615221
9668038
9697703
9927480
10349636
10434059
10441500
10441743
10577388
10662546
10687933
10951186
11042159
11076861
11124466
11217851
11423214
11875276
11950541
11985881
12209837
12466851
12477932
12767889
12787792
14681479
15033168
15146195
15302868
15350283
15357414
15576480
15926914
16141072
16141073
16235133
16529873
16579977
16822977
16845470
16880690
16959763
17114649
17150372
17234811
17409239
17823248
17938178
18075201
18280673
18799693
18848933
18974863
19299509
19339464
20083513
20489728
20534448
20826782
21232211
21267068
21325754
21677750
22047666
22183401
22252018
22349217
22593058
22789621
23568408
23792079
23826306

Gene Ontology  (GO ID)

Biological Process

GO:0006200  ATP catabolic process
GO:0060088  auditory receptor cell stereocilium organization
GO:0070588  calcium ion transmembrane transport
GO:0006816  calcium ion transport
GO:0006812  cation transport
GO:0000902  cell morphogenesis
GO:0006874  cellular calcium ion homeostasis
GO:0021707  cerebellar granule cell differentiation
GO:0021702  cerebellar Purkinje cell differentiation
GO:0021692  cerebellar Purkinje cell layer morphogenesis
GO:0021549  cerebellum development
GO:0046068  cGMP metabolic process
GO:0090102  cochlea development
GO:0051480  cytosolic calcium ion homeostasis
GO:0050910  detection of mechanical stimulus involved in sensory perception of sound
GO:0048839  inner ear development
GO:0042472  inner ear morphogenesis
GO:0060113  inner ear receptor cell differentiation
GO:0034220  ion transmembrane transport
GO:0006811  ion transport
GO:0007595  lactation
GO:0040011  locomotion
GO:0007626  locomotory behavior
GO:0050885  neuromuscular process controlling balance
GO:0030182  neuron differentiation
GO:0006996  organelle organization
GO:0045299  otolith mineralization
GO:0051928  positive regulation of calcium ion transport
GO:0008361  regulation of cell size
GO:0048167  regulation of synaptic plasticity
GO:0007605  sensory perception of sound
GO:0042428  serotonin metabolic process
GO:0050808  synapse organization
GO:0055085  transmembrane transport
GO:0006810  transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0043025  cell soma
GO:0032809  cell soma membrane
GO:0005929  cilium
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0033130  acetylcholine receptor binding
GO:0005524  ATP binding
GO:0005509  calcium ion binding
GO:0030899  calcium-dependent ATPase activity
GO:0005388  calcium-transporting ATPase activity
GO:0005516  calmodulin binding
GO:0019829  cation-transporting ATPase activity
GO:0035254  glutamate receptor binding
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0030165  PDZ domain binding
GO:0008022  protein C-terminus binding