BCL2-associated agonist of cell death

Synonym

BAD, AI325008, Bcl-xL/Bcl-2-associated death promoter, Bbc6, Bcl-associated death promoter, Bbc2, Bcl2 antagonist of cell death, Bad, Bcl-2-binding component 6

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:7.58

cerebellum:7.61

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:7.48

spine:7.73

retina:7.10

eye:7.60

artery/aorta:-

vein:8.15

lymphnode:7.46

peripheral blood:-

spleen:7.44

thymus:-

bone marrow:7.60

adipose:7.67

bone:7.55

skin:7.59

CAGE

cerebrum:2.42

cerebellum:-

brain stem:2.63

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.23

retina:-

eye:-

artery/aorta:2.09

vein:-

lymphnode:2.28

peripheral blood:-

spleen:2.18

thymus:2.44

bone marrow:-

adipose:-

bone:1.69

skin:2.42

RNA-seq

cerebrum:12.49

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:3.30

salivary:-

GeneChip

uterus:7.72

placenta:8.11

prostate:7.58

ovary:7.68

testis:8.50

heart:7.56

muscle:7.24

esophagus:-

stomach:7.93

intestine:7.91

colon:-

liver/hepato:7.68

lung:7.60

bladder:7.83

kidney:7.88

pituitary:7.62

thyroid/parathyroid:-

adrenal gland:7.70

pancreas:7.18

breast:7.66

salivary:7.77

CAGE

uterus:2.54

placenta:2.55

prostate:2.77

ovary:2.55

testis:4.04

heart:-

muscle:-

esophagus:-

stomach:2.79

intestine:2.69

colon:2.88

liver/hepato:2.53

lung:2.46

bladder:2.79

kidney:-

pituitary:2.53

thyroid/parathyroid:-

adrenal gland:2.74

pancreas:2.03

breast:2.55

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:3.34

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:4.29

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007522
Gene ID	12015
Unigene ID	Mm.438704
Probe set ID	1416582_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024959

Orthologous Gene

Human[4]	NM_004322, NM_032989
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0046031	ADP metabolic process
GO:0006915	apoptosis
GO:0046034	ATP metabolic process
GO:0008283	cell proliferation
GO:0060154	cellular process regulating host cell cycle in response to virus
GO:0071316	cellular response to nicotine
GO:0071310	cellular response to organic substance
GO:0019221	cytokine-mediated signaling pathway
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0006007	glucose catabolic process
GO:0042593	glucose homeostasis
GO:0006917	induction of apoptosis
GO:0008625	induction of apoptosis via death domain receptors
GO:0046931	pore complex assembly
GO:0043065	positive regulation of apoptosis
GO:0060139	positive regulation of apoptosis by virus
GO:0045579	positive regulation of B cell differentiation
GO:0043280	positive regulation of caspase activity
GO:0050679	positive regulation of epithelial cell proliferation
GO:0033133	positive regulation of glucokinase activity
GO:0032024	positive regulation of insulin secretion
GO:0010918	positive regulation of mitochondrial membrane potential
GO:0045862	positive regulation of proteolysis
GO:0090200	positive regulation of release of cytochrome c from mitochondria
GO:0045582	positive regulation of T cell differentiation
GO:0042981	regulation of apoptosis
GO:0043281	regulation of caspase activity
GO:0046902	regulation of mitochondrial membrane permeability
GO:0001836	release of cytochrome c from mitochondria
GO:0019050	suppression by virus of host apoptosis

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0005741	mitochondrial outer membrane
GO:0005739	mitochondrion

Molecular Function

GO:0008656	caspase activator activity
GO:0008289	lipid binding
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0043422	protein kinase B binding
GO:0019901	protein kinase binding
GO:0030346	protein phosphatase 2B binding
GO:0019903	protein phosphatase binding

BCL2-associated agonist of cell death

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function