capping protein (actin filament) muscle Z-line, beta

 jump to detail

Synonym

Cappb1, AI325129, 1700120C01Rik, CPB2, CPbeat2, CapZ beta, [b]2 cDNA, CPbeta2, CPbeta1, F-actin capping protein subunit beta, Capzb, CPB1, [b]1 cDNA

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:18.40 brain stem:95.30 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:94.60 retina:64.30 eye:30.40 artery/aorta:- vein:- lymphnode:- peripheral blood:14.40 spleen:13.20 thymus:39.50 bone marrow:- adipose:- bone:37.60 skin:15.80
GeneChip cerebrum:11.06 cerebellum:10.77 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.69 spine:11.13 retina:10.16 eye:10.81 artery/aorta:- vein:11.42 lymphnode:11.91 peripheral blood:- spleen:12.09 thymus:- bone marrow:11.69 adipose:10.82 bone:11.69 skin:11.38
CAGE cerebrum:4.77 cerebellum:- brain stem:4.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.91 retina:- eye:- artery/aorta:4.88 vein:- lymphnode:5.25 peripheral blood:- spleen:4.84 thymus:4.80 bone marrow:- adipose:- bone:5.14 skin:4.94
RNA-seq cerebrum:53.06 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:174.50 placenta:13.80 prostate:61.80 ovary:- testis:14.80 heart:37.20 muscle:- esophagus:- stomach:- intestine:- colon:35.20     liver/hepato:9.10        lung:30.10    bladder:- kidney:- pituitary:25.80 thyroid/parathyroid:- adrenal gland:- pancreas:18.80 breast:42.40 salivary:-
GeneChip uterus:12.02 placenta:11.48 prostate:11.02 ovary:11.53 testis:10.41 heart:11.20 muscle:11.85 esophagus:- stomach:11.69 intestine:11.78 colon:- liver/hepato:10.12 lung:11.59 bladder:11.79 kidney:10.40 pituitary:10.83 thyroid/parathyroid:- adrenal gland:11.35 pancreas:9.84 breast:11.32 salivary:10.83
CAGE uterus:5.23 placenta:5.33 prostate:4.71 ovary:4.90 testis:7.22 heart:- muscle:- esophagus:- stomach:5.59 intestine:5.10 colon:5.52     liver/hepato:4.67    lung:5.11 bladder:5.40 kidney:- pituitary:4.45 thyroid/parathyroid:- adrenal gland:4.88 pancreas:4.13 breast:4.90 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:64.85 esophagus:- stomach:- intestine:- colon:-     liver/hepato:18.69        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001037761
Gene ID 12345
Unigene ID Mm.294503
Probe set ID 1424168_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028745

Orthologous Gene

Human[3]  NM_001206540, NM_001206541, NM_004930
Rat[1]  NM_001005903, NM_001206541, NM_004930

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7929588
8954774
9184090
9224952
10349636
10512203
10601341
10922068
11001587
11042159
11076861
11217851
11517222
11604420
12089068
12466851
12477932
12520002
12904583
14610273
15294161
15782199
15800061
15840001
15850461
16141072
16141073
16512683
16602821
16717059
16944949
16959763
17656356
17967808
18723693
18799693
19075228
19341723
19806181
20884878
20969875
21267068
21589869
21677750
22155006
22710966
22918941
24457600
24614889

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0051693  actin filament capping
GO:0051016  barbed-end actin filament capping
GO:0030030  cell projection organization
GO:0007010  cytoskeleton organization
GO:0030032  lamellipodium assembly
GO:0048747  muscle fiber development
GO:0031115  negative regulation of microtubule polymerization
GO:0031175  neuron projection development
GO:0022604  regulation of cell morphogenesis
GO:0090036  regulation of protein kinase C signaling cascade

Cellular Component

GO:0001669  acrosomal vesicle
GO:0030863  cortical cytoskeleton
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0008290  F-actin capping protein complex
GO:0014704  intercalated disc
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0071203  WASH complex
GO:0030018  Z disc

Molecular Function

GO:0003779  actin binding
GO:0051015  actin filament binding
GO:0048487  beta-tubulin binding
GO:0005515  protein binding