cystathionine beta-synthase

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Synonym

MGC18856, AI047524, AI303044, Cbs, cystathionine beta-synthase, HIP4, MGC37300, MGC18895

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:67.70

cerebellum:128.90

brain stem:127.10

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:47.30

retina:-

eye:15.20

artery/aorta:-

vein:-

lymphnode:10.80

peripheral blood:-

spleen:92.20

thymus:-

bone marrow:-

adipose:-

bone:62.60

skin:39.60

GeneChip

cerebrum:7.18

cerebellum:7.59

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.86

spine:7.97

retina:5.84

eye:6.50

artery/aorta:-

vein:5.57

lymphnode:5.54

peripheral blood:-

spleen:5.82

thymus:-

bone marrow:5.48

adipose:6.23

bone:5.21

skin:7.53

CAGE

cerebrum:3.21

cerebellum:-

brain stem:3.39

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.55

retina:-

eye:-

artery/aorta:0.77

vein:-

lymphnode:0

peripheral blood:-

spleen:0.16

thymus:0

bone marrow:-

adipose:-

bone:0.63

skin:3.13

RNA-seq

cerebrum:7.03

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:30.90

ovary:-

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:88.10

liver/hepato:543

lung:30.10

bladder:-

kidney:274

pituitary:12.90

thyroid/parathyroid:-

adrenal gland:-

pancreas:112.60

breast:42.40

salivary:-

GeneChip

uterus:6.55

placenta:5.54

prostate:9.08

ovary:9.44

testis:6.03

heart:6.39

muscle:6.22

esophagus:-

stomach:8.12

intestine:7.29

colon:-

liver/hepato:11.72

lung:7.05

bladder:5.88

kidney:10.46

pituitary:6.31

thyroid/parathyroid:-

adrenal gland:6.01

pancreas:10.99

breast:5.98

salivary:5.88

CAGE

uterus:2.74

placenta:0

prostate:3.44

ovary:4.32

testis:0.75

heart:-

muscle:-

esophagus:-

stomach:2.16

intestine:0.23

colon:2.00

liver/hepato:5.04

lung:1.28

bladder:0.57

kidney:-

pituitary:1.48

thyroid/parathyroid:-

adrenal gland:1.22

pancreas:5.41

breast:1.47

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:0.81

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:52.84

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_144855
Gene ID	12411
Unigene ID	Mm.206417
Probe set ID	1423844_s_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024039

Orthologous Gene

Human[1]	NM_000071, NM_001178008, NM_001178009
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0001974	blood vessel remodeling
GO:0060351	cartilage development involved in endochondral bone morphogenesis
GO:0008652	cellular amino acid biosynthetic process
GO:0071456	cellular response to hypoxia
GO:0021587	cerebellum morphogenesis
GO:0019344	cysteine biosynthetic process
GO:0006535	cysteine biosynthetic process from serine
GO:0019343	cysteine biosynthetic process via cystathionine
GO:0001958	endochondral ossification
GO:0043418	homocysteine catabolic process
GO:0050667	homocysteine metabolic process
GO:0070814	hydrogen sulfide biosynthetic process
GO:0019448	L-cysteine catabolic process
GO:0006565	L-serine catabolic process
GO:0006563	L-serine metabolic process
GO:0060135	maternal process involved in female pregnancy
GO:0043066	negative regulation of apoptosis
GO:0050880	regulation of blood vessel size
GO:0030823	regulation of cGMP metabolic process
GO:0043506	regulation of JUN kinase activity
GO:0051593	response to folic acid
GO:0006801	superoxide metabolic process
GO:0019346	transsulfuration

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043231	intracellular membrane-bounded organelle
GO:0005730	nucleolus
GO:0005634	nucleus

Molecular Function

GO:0030554	adenyl nucleotide binding
GO:0004122	cystathionine beta-synthase activity
GO:0004124	cysteine synthase activity
GO:0019899	enzyme binding
GO:0020037	heme binding
GO:0016829	lyase activity
GO:0046872	metal ion binding
GO:0042803	protein homodimerization activity
GO:0030170	pyridoxal phosphate binding
GO:0016740	transferase activity
GO:0031625	ubiquitin protein ligase binding

cystathionine beta-synthase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function