pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1

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Synonym

Pcbd, Pcbd1, PHS, DCoH, Phenylalanine hydroxylase-stimulating protein, Dimerization cofactor of HNF1, PCD, Pterin carbinolamine dehydratase, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin-4-alpha-carbinolamine dehydratase, Dcoh

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.47 cerebellum:7.31 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.30 spine:7.97 retina:7.83 eye:8.19 artery/aorta:- vein:6.94 lymphnode:6.02 peripheral blood:- spleen:6.19 thymus:- bone marrow:6.06 adipose:7.91 bone:6.39 skin:6.82
CAGE cerebrum:2.02 cerebellum:- brain stem:3.32 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.83 retina:- eye:- artery/aorta:0.62 vein:- lymphnode:0.23 peripheral blood:- spleen:1.06 thymus:0.27 bone marrow:- adipose:- bone:0 skin:1.60
RNA-seq cerebrum:5.95 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.96 placenta:8.68 prostate:7.74 ovary:7.33 testis:6.64 heart:6.83 muscle:6.62 esophagus:- stomach:9.68 intestine:9.58 colon:- liver/hepato:12.08 lung:8.19 bladder:7.55 kidney:12.07 pituitary:9.23 thyroid/parathyroid:- adrenal gland:8.40 pancreas:11.76 breast:6.75 salivary:6.92
CAGE uterus:2.00 placenta:3.36 prostate:3.18 ovary:2.35 testis:0.75 heart:- muscle:- esophagus:- stomach:4.87 intestine:4.27 colon:4.43     liver/hepato:6.50    lung:2.59 bladder:2.87 kidney:- pituitary:3.94 thyroid/parathyroid:- adrenal gland:2.98 pancreas:5.76 breast:1.69 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.83 esophagus:- stomach:- intestine:- colon:-     liver/hepato:75.53        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_025273
Gene ID 13180
Unigene ID Mm.394730
Probe set ID 1418713_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020098

Orthologous Gene

Human[1]  NM_000281
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1763325
8486378
8889548
9653653
10349636
11042159
11076861
11217851
12011081
12466851
12477932
14610273
15182178
15489334
16141072
16141073
16602821
18287559
18346943
18554416
20059953
20211142
21267068
21362171
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0055114  oxidation reduction
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051291  protein heterooligomerization
GO:0051289  protein homotetramerization
GO:0043496  regulation of protein homodimerization activity
GO:0006355  regulation of transcription, DNA-dependent
GO:0006729  tetrahydrobiopterin biosynthetic process
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0008124  4-alpha-hydroxytetrahydrobiopterin dehydratase activity
GO:0042802  identical protein binding
GO:0016829  lyase activity
GO:0004505  phenylalanine 4-monooxygenase activity
GO:0005515  protein binding
GO:0003713  transcription coactivator activity