DEAD (Asp-Glu-Ala-Asp) box polypeptide 6

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Synonym

mRCK/P54, Hlr2, ATP-dependent RNA helicase p54, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, DEAD box protein 6, p54, HLR2, Rck, Ddx6, rck, Oncogene RCK homolog, Probable ATP-dependent RNA helicase DDX6, E230023J21Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:31.30 cerebellum:36.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:57.30 spine:47.30 retina:96.40 eye:45.60 artery/aorta:168.80 vein:- lymphnode:75.60 peripheral blood:43.10 spleen:118.50 thymus:69.20 bone marrow:64.10 adipose:- bone:87.70 skin:23.80
GeneChip cerebrum:10.15 cerebellum:9.95 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.17 spine:9.64 retina:9.91 eye:9.71 artery/aorta:- vein:10.20 lymphnode:10.86 peripheral blood:- spleen:10.80 thymus:- bone marrow:10.71 adipose:9.85 bone:10.59 skin:10.63
CAGE cerebrum:4.10 cerebellum:- brain stem:3.83 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.91 retina:- eye:- artery/aorta:3.73 vein:- lymphnode:4.46 peripheral blood:- spleen:3.73 thymus:4.21 bone marrow:- adipose:- bone:3.73 skin:3.76
RNA-seq cerebrum:4.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:27.60 prostate:123.50 ovary:34.50 testis:7.40 heart:55.80 muscle:142 esophagus:- stomach:327.30 intestine:295.80 colon:70.50     liver/hepato:45.30        lung:40.20    bladder:66.20 kidney:120.90 pituitary:77.50 thyroid/parathyroid:112.50 adrenal gland:- pancreas:103.20 breast:153.40 salivary:-
GeneChip uterus:10.62 placenta:10.24 prostate:10.96 ovary:10.48 testis:8.80 heart:9.48 muscle:10.05 esophagus:- stomach:10.12 intestine:9.88 colon:- liver/hepato:9.56 lung:10.62 bladder:10.63 kidney:9.47 pituitary:10.84 thyroid/parathyroid:- adrenal gland:10.48 pancreas:8.32 breast:10.26 salivary:10.92
CAGE uterus:3.95 placenta:3.65 prostate:3.83 ovary:3.99 testis:3.47 heart:- muscle:- esophagus:- stomach:3.45 intestine:3.37 colon:3.46     liver/hepato:3.58    lung:4.06 bladder:4.02 kidney:- pituitary:4.13 thyroid/parathyroid:- adrenal gland:3.79 pancreas:3.45 breast:3.80 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:3.30 esophagus:- stomach:- intestine:- colon:-     liver/hepato:4.64        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001110826
Gene ID 13209
Unigene ID Mm.267061
Probe set ID 1434697_at  [Mouse430_2]
Ensembl ID ENSMUSG00000032097

Orthologous Gene

Human[1]  NM_004397
Rat[1]  NM_004397

Chromosomal Region

9A5.2  [44,412,975  -  44,448,814]

Gene Family (Interpro ID)

IPR014001  DEAD-like helicase, N-terminal
IPR014021  Helicase, superfamily 1/2, ATP-binding domain

Link to Pubmed  (Pubmed ID)

8543178
8786135
8995487
9883581
10349636
11042159
11076861
11217851
12466851
12477932
15489334
15906376
15979417
16141072
16141073
16618942
16944949
18769115
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0033962  cytoplasmic mRNA processing body assembly

Cellular Component

GO:0005737  cytoplasm
GO:0000932  cytoplasmic mRNA processing body
GO:0016442  RNA-induced silencing complex
GO:0010494  stress granule

Molecular Function

GO:0005524  ATP binding
GO:0008026  ATP-dependent helicase activity
GO:0004386  helicase activity
GO:0016787  hydrolase activity
GO:0003676  nucleic acid binding
GO:0000166  nucleotide binding
GO:0003723  RNA binding