discs, large homolog 1 (Drosophila)

Synonym

SAP-97, KIAA4187, Embryo-dlg/synapse-associated protein 97, E-dlg/SAP97, B130052P05Rik, Synapse-associated protein 97, SAP97, Dlgh1, Disks large homolog 1, Dlg1, discs, large homolog 1 (Drosophila), mKIAA4187

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:10.62

cerebellum:10.52

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:7.94

spine:9.81

retina:10.49

eye:10.46

artery/aorta:-

vein:10.53

lymphnode:9.50

peripheral blood:-

spleen:9.72

thymus:-

bone marrow:9.22

adipose:9.44

bone:9.54

skin:9.82

CAGE

cerebrum:3.72

cerebellum:-

brain stem:3.61

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.63

retina:-

eye:-

artery/aorta:3.44

vein:-

lymphnode:3.25

peripheral blood:-

spleen:3.03

thymus:2.89

bone marrow:-

adipose:-

bone:2.88

skin:3.83

RNA-seq

cerebrum:6.07

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:10.08

placenta:9.55

prostate:10.67

ovary:9.73

testis:7.42

heart:9.64

muscle:9.85

esophagus:-

stomach:9.81

intestine:9.64

colon:-

liver/hepato:9.21

lung:10.12

bladder:10.54

kidney:9.42

pituitary:9.75

thyroid/parathyroid:-

adrenal gland:9.95

pancreas:9.93

breast:9.83

salivary:10.59

CAGE

uterus:3.45

placenta:3.36

prostate:3.26

ovary:3.30

testis:2.12

heart:-

muscle:-

esophagus:-

stomach:3.29

intestine:3.06

colon:3.24

liver/hepato:3.30

lung:3.40

bladder:3.84

kidney:-

pituitary:3.47

thyroid/parathyroid:-

adrenal gland:3.47

pancreas:4.15

breast:3.75

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:3.82

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:4.48

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007862
Gene ID	13383
Unigene ID	-
Probe set ID	1415691_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022770

Orthologous Gene

Human[8]	NM_001098424, NM_001204386, NM_001204387, NM_001204388, NM_004087
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR008144	Guanylate kinase
IPR008145	Guanylate kinase/L-type calcium channel
IPR004172	L27

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0007015	actin filament organization
GO:0032147	activation of protein kinase activity
GO:0042982	amyloid precursor protein metabolic process
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0016337	cell-cell adhesion
GO:0030866	cortical actin cytoskeleton organization
GO:0048704	embryonic skeletal system morphogenesis
GO:0001935	endothelial cell proliferation
GO:0001771	formation of immunological synapse
GO:0060022	hard palate development
GO:0002088	lens development in camera-type eye
GO:0031579	membrane raft organization
GO:0050680	negative regulation of epithelial cell proliferation
GO:0045930	negative regulation of mitotic cell cycle
GO:0042130	negative regulation of T cell proliferation
GO:0030432	peristalsis
GO:0030838	positive regulation of actin filament polymerization
GO:0008284	positive regulation of cell proliferation
GO:0048639	positive regulation of developmental growth
GO:0090004	positive regulation of establishment of protein localization in plasma membrane
GO:0040018	positive regulation of multicellular organism growth
GO:0043268	positive regulation of potassium ion transport
GO:0008104	protein localization
GO:0042391	regulation of membrane potential
GO:0032880	regulation of protein localization
GO:0048608	reproductive structure development
GO:0048745	smooth muscle tissue development
GO:0042110	T cell activation
GO:0002369	T cell cytokine production
GO:0070830	tight junction assembly
GO:0048729	tissue morphogenesis
GO:0001657	ureteric bud development

Cellular Component

GO:0009925	basal plasma membrane
GO:0016323	basolateral plasma membrane
GO:0030054	cell junction
GO:0031253	cell projection membrane
GO:0005913	cell-cell adherens junction
GO:0005911	cell-cell junction
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0001772	immunological synapse
GO:0009898	internal side of plasma membrane
GO:0043219	lateral loop
GO:0016328	lateral plasma membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005874	microtubule
GO:0031594	neuromuscular junction
GO:0043005	neuron projection
GO:0033268	node of Ranvier
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0042734	presynaptic membrane
GO:0045202	synapse
GO:0030315	T-tubule
GO:0005923	tight junction

Molecular Function

GO:0035255	ionotropic glutamate receptor binding
GO:0031434	mitogen-activated protein kinase kinase binding
GO:0030165	PDZ domain binding
GO:0019902	phosphatase binding
GO:0015459	potassium channel regulator activity
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0032947	protein complex scaffold
GO:0019901	protein kinase binding

discs, large homolog 1 (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function