engulfment and cell motility 1, ced-12 homolog (C. elegans)

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Synonym

CED-12 homolog, Elmo1, CED-12, mKIAA0281, C230095H21Rik, KIAA0281, 6330578D22Rik, AI173001, Engulfment and cell motility protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:41.70 cerebellum:92.10 brain stem:222.50 corpus callosum/glia:- pineal gland:- peripheral nerve:114.70 spine:47.30 retina:- eye:30.40 artery/aorta:- vein:- lymphnode:43.20 peripheral blood:172.50 spleen:26.30 thymus:49.40 bone marrow:25.60 adipose:- bone:25 skin:15.80
GeneChip cerebrum:6.88 cerebellum:7.01 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.45 spine:6.34 retina:4.99 eye:5.31 artery/aorta:- vein:5.19 lymphnode:7.93 peripheral blood:- spleen:6.23 thymus:- bone marrow:6.96 adipose:5.21 bone:5.59 skin:4.81
CAGE cerebrum:4.77 cerebellum:- brain stem:5.46 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.07 retina:- eye:- artery/aorta:3.62 vein:- lymphnode:5.87 peripheral blood:- spleen:4.41 thymus:4.82 bone marrow:- adipose:- bone:4.81 skin:3.73
RNA-seq cerebrum:28.24 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:27.60 prostate:- ovary:23 testis:- heart:- muscle:- esophagus:- stomach:32.70 intestine:- colon:17.60     liver/hepato:9.10        lung:30.10    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:46.90 breast:42.40 salivary:-
GeneChip uterus:5.18 placenta:5.96 prostate:4.90 ovary:5.10 testis:6.46 heart:5.23 muscle:5.30 esophagus:- stomach:5.21 intestine:5.20 colon:- liver/hepato:5.15 lung:5.35 bladder:4.81 kidney:5.06 pituitary:5.02 thyroid/parathyroid:- adrenal gland:4.72 pancreas:5.57 breast:5.13 salivary:4.90
CAGE uterus:3.62 placenta:3.68 prostate:3.22 ovary:4.04 testis:2.82 heart:- muscle:- esophagus:- stomach:3.67 intestine:3.54 colon:4.24     liver/hepato:1.94    lung:4.66 bladder:3.39 kidney:- pituitary:3.11 thyroid/parathyroid:- adrenal gland:3.70 pancreas:2.83 breast:3.43 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.87 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.29        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_198093
Gene ID 140580
Unigene ID Mm.342392
Probe set ID 1450208_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000041112

Orthologous Gene

Human[3]  NM_001039459, NM_001206480, NM_001206482, NM_014800, NM_130442
Rat[1]  NM_001108415, NM_001206480, NM_001206482, NM_014800, NM_130442

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
11595183
12466851
12477932
14610273
15102471
15489334
16141072
16141073
16377631
16443196
16602821
17582329
17960134
17967808
18799693
20844538
21267068
21677750
21804544
23273896
24154525

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0030029  actin filament-based process
GO:0006915  apoptosis
GO:0006928  cellular component movement
GO:0006909  phagocytosis
GO:0006911  phagocytosis, engulfment
GO:0016601  Rac protein signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0017124  SH3 domain binding