FAT tumor suppressor homolog 1 (Drosophila)

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Synonym

mFat1, 2310038E12Rik, AU023433, Fath, Fat1, fat tumor suppressor homolog (Drosophila)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:18.40 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:47.30 retina:64.30 eye:30.40 artery/aorta:675.10 vein:- lymphnode:43.20 peripheral blood:14.40 spleen:92.20 thymus:168 bone marrow:38.50 adipose:- bone:137.80 skin:142.50
GeneChip nodata
CAGE nodata
RNA-seq cerebrum:3.37 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:7.40 heart:55.80 muscle:177.50 esophagus:- stomach:32.70 intestine:332.80 colon:35.20     liver/hepato:-        lung:30.10    bladder:397.10 kidney:16.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:39.20 salivary:-
GeneChip nodata
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.87 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.52        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001081286
Gene ID 14107
Unigene ID Mm.273659
Probe set ID -
Ensembl ID ENSMUSG00000070047

Orthologous Gene

Human[1]  NM_005245
Rat [0]  

Chromosomal Region

8B1.1  [46,035,562  -  46,137,611]

Gene Family (Interpro ID)

IPR002126  Cadherin
IPR015919  Cadherin-like
IPR008985  Concanavalin A-like lectin/glucanase
IPR013320  Concanavalin A-like lectin/glucanase, subgroup
IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3
IPR001791  Laminin G

Link to Pubmed  (Pubmed ID)

7604039
9107695
9680377
10349636
10725249
10741417
10922068
11042159
11076861
11217851
11431694
12466851
12477932
12520002
12724416
12904583
15148305
15744052
16059920
16141072
16141073
16682528
17500054
19131340
21267068
22510986
22959770
23785297
23994161

Gene Ontology  (GO ID)

Biological Process

GO:0007015  actin filament organization
GO:0007155  cell adhesion
GO:0016337  cell-cell adhesion
GO:0007163  establishment or maintenance of cell polarity

Cellular Component

GO:0030054  cell junction
GO:0005911  cell-cell junction
GO:0030175  filopodium
GO:0016021  integral to membrane
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding