Fyn proto-oncogene

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Synonym

p59-Fyn, AI448320, Src Kinase p59, Fyn proto-oncogene, AW552119, Proto-oncogene tyrosine-protein kinase Fyn, Fyn, MGC115870

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:86.80 cerebellum:55.30 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:94.60 retina:96.40 eye:15.20 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:1351.40 spleen:144.80 thymus:187.70 bone marrow:64.10 adipose:- bone:- skin:71.30
GeneChip cerebrum:9.67 cerebellum:9.64 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.06 spine:9.65 retina:7.33 eye:6.91 artery/aorta:- vein:8.60 lymphnode:10.08 peripheral blood:- spleen:9.90 thymus:- bone marrow:8.38 adipose:7.55 bone:8.49 skin:7.71
CAGE cerebrum:4.69 cerebellum:- brain stem:4.46 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.56 retina:- eye:- artery/aorta:3.61 vein:- lymphnode:5.19 peripheral blood:- spleen:4.10 thymus:4.84 bone marrow:- adipose:- bone:4.05 skin:4.44
RNA-seq cerebrum:17.65 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:30.90 ovary:149.40 testis:14.80 heart:37.20 muscle:35.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:18.10        lung:50.20    bladder:- kidney:8.10 pituitary:12.90 thyroid/parathyroid:- adrenal gland:- pancreas:37.50 breast:49 salivary:-
GeneChip uterus:9.61 placenta:8 prostate:6.92 ovary:9.30 testis:8.44 heart:9.03 muscle:7.60 esophagus:- stomach:7.12 intestine:6.95 colon:- liver/hepato:7.31 lung:8.81 bladder:7.44 kidney:6.95 pituitary:8.50 thyroid/parathyroid:- adrenal gland:9.47 pancreas:8.87 breast:7.87 salivary:6.97
CAGE uterus:4.27 placenta:3.63 prostate:2.06 ovary:4.40 testis:3.89 heart:- muscle:- esophagus:- stomach:2.26 intestine:2.65 colon:3.21     liver/hepato:3.17    lung:4.17 bladder:3.07 kidney:- pituitary:3.88 thyroid/parathyroid:- adrenal gland:4.25 pancreas:3.10 breast:3.13 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.89 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.95        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_001122893
Gene ID 14360
Unigene ID Mm.4848
Probe set ID 1417558_at  [Mouse430_2]
Ensembl ID ENSMUSG00000019843

Orthologous Gene

Human[8]  NM_001242779, NM_002037, NM_153047, NM_153048
Rat[1]  NM_012755, NM_002037, NM_153047, NM_153048

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1337939
1361685
1370487
1387588
1409582
1427822
1516132
1975791
2015626
2404338
2488273
3099169
7493751
7499280
7509042
7536925
7544314
7557381
7617039
7650487
7705639
7723633
7730365
7799925
7877449
7884321
7916323
7958873
7962063
7980442
8007959
8034026
8058305
8175795
8196616
8226859
8235598
8247536
8264796
8402898
8413237
8441403
8535092
8551236
8562954
8570184
8605874
8631859
8635998
8641568
8643689
8655574
8700547
8738145
8812055
8861907
8864276
8889548
8904782
8934569
8934570
8943574
8981455
8983085
9045930
9062339
9079653
9114065
9115297
9151674
9177270
9185665
9201723
9210408
9276618
9278347
9294143
9294206
9315092
9381182
9396778
9425184
9507006
9535845
9605142
9653087
9655502
9658338
9712716
9774338
9890970
9892651
9895129
9973382
9987012
10051318
10087297
10228160
10349636
10453000
10464165
10489260
10510341
10523617
10575223
10612399
10635317
10675790
10684862
10713104
10739664
10802341
10829070
10844001
10869499
10872802
10922068
10935514
11005864
11007902
11024032
11027535
11034371
11042159
11076861
11093170
11106751
11110698
11114734
11130076
11160194
11166177
11175854
11180952
11217851
11245687
11287076
11306441
11312300
11423094
11468287
11477403
11489976
11676481
11707774
11711534
11751285
11826099
11834300
11870621
12077322
12089510
12218089
12218114
12239221
12359721
12372285
12374739
12399115
12466851
12471123
12477932
12526739
12526740
12538589
12545173
12545174
12563261
12668668
12732664
12808452
12921535
13129922
13129934
14559149
14610273
14645715
14651920
14681479
14685278
14707117
14757743
14761972
15034040
15049519
15073522
15102471
15128794
15140940
15154672
15210764
15220932
15240808
15297464
15465914
15477350
15485773
15486073
15489334
15494732
15494734
15519685
15528192
15537652
15539155
15539156
15542585
15548669
15549774
15623578
15634346
15711562
15713745
15716419
15735648
15738056
15782199
15813945
15814670
15851519
15902435
15998796
15998803
16101815
16115884
16141072
16141073
16162939
16190898
16262245
16272308
16301670
16316995
16337776
16339032
16339530
16407246
16425036
16427614
16438943
16442778
16456001
16540575
16547257
16585062
16602821
16628251
16687575
16709819
16723512
16751367
16754717
16765915
16777849
16841086
16847311
16859680
16880206
16882656
16899217
16908977
16966372
16979591
17045972
17046829
17202343
17210649
17213284
17241158
17277164
17290413
17392475
17394141
17449027
17460065
17475794
17488639
17521824
17579091
17599905
17623670
17623777
17675483
17845201
17878361
17923684
18031696
18046458
18089558
18095272
18096814
18194650
18255094
18301737
18339867
18354028
18403215
18430780
18482989
18490510
18499741
18550847
18632659
18636972
18647647
18660530
18684920
18691323
18832694
18854310
18922801
18948260
19000718
19016778
19118543
19141671
19294646
19304944
19362019
19363790
19403835
19420001
19439358
19587372
19668367
19734451
19776266
19812040
19888448
19900187
19904769
19917692
19917775
19956733
19966925
20004975
20038804
20043875
20080640
20101614
20126650
20142099
20176789
20200355
20233604
20304029
20335178
20346773
20372074
20398064
20495068
20506281
20544909
20571036
20591331
20606012
20668219
20685990
20717919
20814235
20841362
20850416
20978343
21054385
21088116
21097520
21098033
21228179
21267068
21339332
21427288
21464326
21534960
21592972
21630272
21653832
21677750
21692989
21705469
21741124
21757751
21829547
21871204
21872217
21881001
21915273
21918125
21946561
22057277
22189847
22386537
22387224
22393150
22437915
22450804
22539787
22564682
22663768
22683124
22745922
22820466
22971575
23012656
23127881
23169819
23284724
23321073
23427257
23430111
23438599
23593269
23602477
23616926
23967147
24036998
24045941
24312371
24312422
24440149

Gene Ontology  (GO ID)

Biological Process

GO:0050798  activated T cell proliferation
GO:0007166  cell surface receptor linked signal transduction
GO:0048813  dendrite morphogenesis
GO:0050966  detection of mechanical stimulus involved in sensory perception of pain
GO:0030900  forebrain development
GO:0007275  multicellular organismal development
GO:0042552  myelination
GO:0010629  negative regulation of gene expression
GO:0042177  negative regulation of protein catabolic process
GO:0001764  neuron migration
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0010976  positive regulation of neuron projection development
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0008360  regulation of cell shape
GO:0045471  response to ethanol
GO:0050852  T cell receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005768  endosome
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0014069  postsynaptic density

Molecular Function

GO:0005524  ATP binding
GO:0042609  CD4 receptor binding
GO:0042610  CD8 receptor binding
GO:0046875  ephrin receptor binding
GO:0001948  glycoprotein binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0046872  metal ion binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0000166  nucleotide binding
GO:0051428  peptide hormone receptor binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0005102  receptor binding
GO:0042608  T cell receptor binding
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0015631  tubulin binding