growth arrest specific 1

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Synonym

Gas-1, AW554192, growth arrest specific 1, Growth-arrest-specific protein 1 precursor, Gas1, GAS-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26 cerebellum:- brain stem:31.80 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:57.30 spine:- retina:- eye:38 artery/aorta:253.20 vein:- lymphnode:10.80 peripheral blood:- spleen:- thymus:138.30 bone marrow:- adipose:- bone:- skin:110.80
GeneChip cerebrum:8.05 cerebellum:9.07 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.23 spine:8.17 retina:9.81 eye:11.58 artery/aorta:- vein:12.55 lymphnode:8.44 peripheral blood:- spleen:8.57 thymus:- bone marrow:7.60 adipose:10.11 bone:8.88 skin:11.37
CAGE cerebrum:2.11 cerebellum:- brain stem:1.64 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.88 retina:- eye:- artery/aorta:3.88 vein:- lymphnode:0.57 peripheral blood:- spleen:1.94 thymus:2.49 bone marrow:- adipose:- bone:2.45 skin:3.72
RNA-seq cerebrum:2.25 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:218.10 placenta:13.80 prostate:92.60 ovary:46 testis:7.40 heart:74.40 muscle:- esophagus:- stomach:- intestine:37 colon:-     liver/hepato:27.20        lung:10    bladder:330.90 kidney:24.20 pituitary:12.90 thyroid/parathyroid:112.50 adrenal gland:- pancreas:75.10 breast:32.60 salivary:162
GeneChip uterus:12.09 placenta:8.69 prostate:9.91 ovary:11.76 testis:7.50 heart:10.36 muscle:10.08 esophagus:- stomach:9.67 intestine:8.97 colon:- liver/hepato:8.95 lung:9.40 bladder:12.67 kidney:9.69 pituitary:8.38 thyroid/parathyroid:- adrenal gland:10.03 pancreas:9.14 breast:10.80 salivary:10.68
CAGE uterus:4.85 placenta:2.58 prostate:3.70 ovary:4.30 testis:0.99 heart:- muscle:- esophagus:- stomach:3.36 intestine:2.45 colon:2.19     liver/hepato:3.05    lung:2.83 bladder:4.80 kidney:- pituitary:1.56 thyroid/parathyroid:- adrenal gland:3.28 pancreas:3.21 breast:3.63 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:3.19 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.03        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_008086
Gene ID 14451
Unigene ID Mm.22701
Probe set ID 1416855_at  [Mouse430_2]
Ensembl ID ENSMUSG00000052957

Orthologous Gene

Human[2]  NM_002048
Rat[2]  NM_002048

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1347472
1427878
1505026
2569712
3409319
8127893
8226788
8307588
8666395
8889548
9188486
9189272
9671732
9932288
10349636
10922068
10996315
10996316
11042159
11076861
11217851
11231094
11356029
11456441
11456442
11572986
11906213
11955608
12399319
12466851
12477932
14681479
15070677
15151988
15459106
15489334
15760903
16141072
16141073
16168717
16551639
16602821
17504940
17504941
17525797
18539269
18554416
18981472
19211681
19449303
19478089
21150899
21440680
21664576
21664577
21802063
21820049
21858068
22898775
23429478
23813868

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0043010  camera-type eye development
GO:0007049  cell cycle
GO:0007050  cell cycle arrest
GO:0045165  cell fate commitment
GO:0021587  cerebellum morphogenesis
GO:0048589  developmental growth
GO:0021904  dorsal/ventral neural tube patterning
GO:0009953  dorsal/ventral pattern formation
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0048598  embryonic morphogenesis
GO:0048706  embryonic skeletal system development
GO:0048592  eye morphogenesis
GO:0042474  middle ear morphogenesis
GO:0043066  negative regulation of apoptosis
GO:0030308  negative regulation of cell growth
GO:0050680  negative regulation of epithelial cell proliferation
GO:0045930  negative regulation of mitotic cell cycle
GO:0010955  negative regulation of protein maturation by peptide bond cleavage
GO:0045879  negative regulation of smoothened signaling pathway
GO:0042476  odontogenesis
GO:0042473  outer ear morphogenesis
GO:0060021  palate development
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045880  positive regulation of smoothened signaling pathway
GO:0012501  programmed cell death
GO:0060628  regulation of ER to Golgi vesicle-mediated transport
GO:0008589  regulation of smoothened signaling pathway

Cellular Component

GO:0031225  anchored to membrane
GO:0046658  anchored to plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding