GLI-Kruppel family member GLI1

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Synonym

Gli1, Zfp-5, Glioma-associated oncogene homolog, Zfp5, Zinc finger protein GLI1, Gli, AV235269, GLI-Kruppel family member GLI1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13.90 cerebellum:92.10 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:114.70 spine:47.30 retina:32.10 eye:38 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:26.30 thymus:- bone marrow:- adipose:- bone:37.60 skin:71.30
GeneChip cerebrum:4.67 cerebellum:5.99 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.72 spine:5.05 retina:4.78 eye:5.41 artery/aorta:- vein:6.37 lymphnode:5.29 peripheral blood:- spleen:5.05 thymus:- bone marrow:4.89 adipose:5.28 bone:4.98 skin:6.41
CAGE cerebrum:1.56 cerebellum:- brain stem:0.81 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.91 retina:- eye:- artery/aorta:1.46 vein:- lymphnode:0.57 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:2.53
RNA-seq cerebrum:1.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:7.40 heart:- muscle:- esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:-        lung:10    bladder:132.40 kidney:- pituitary:38.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:8.59 placenta:5.22 prostate:5.64 ovary:7.50 testis:5.11 heart:5.46 muscle:5.51 esophagus:- stomach:5.62 intestine:5.59 colon:- liver/hepato:4.88 lung:5.51 bladder:7.17 kidney:4.87 pituitary:5.32 thyroid/parathyroid:- adrenal gland:5.72 pancreas:5.83 breast:4.92 salivary:5.01
CAGE uterus:2.69 placenta:0.43 prostate:1.02 ovary:2.30 testis:0.45 heart:- muscle:- esophagus:- stomach:1.35 intestine:0.58 colon:1.27     liver/hepato:0    lung:1.17 bladder:2.12 kidney:- pituitary:1.75 thyroid/parathyroid:- adrenal gland:1.34 pancreas:0 breast:0.34 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.47 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_010296
Gene ID 14632
Unigene ID Mm.391450
Probe set ID 1449058_at  [Mouse430_2]
Ensembl ID ENSMUSG00000025407

Orthologous Gene

Human[3]  NM_001160045, NM_001167609, NM_005269
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

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Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0021696  cerebellar cortex morphogenesis
GO:0009953  dorsal/ventral pattern formation
GO:0009913  epidermal cell differentiation
GO:0030324  lung development
GO:0007275  multicellular organismal development
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0060032  notochord regression
GO:0001649  osteoblast differentiation
GO:0021983  pituitary gland development
GO:0008284  positive regulation of cell proliferation
GO:0045740  positive regulation of DNA replication
GO:0045880  positive regulation of smoothened signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0009954  proximal/distal pattern formation
GO:0006355  regulation of transcription, DNA-dependent
GO:0007165  signal transduction
GO:0007224  smoothened signaling pathway
GO:0021938  smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation
GO:0007283  spermatogenesis
GO:0006351  transcription, DNA-dependent
GO:0007418  ventral midline development

Cellular Component

GO:0005929  cilium
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0046872  metal ion binding
GO:0008017  microtubule binding
GO:0003676  nucleic acid binding
GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding