glycine receptor, alpha 1 subunit

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Synonym

B230397M16Rik, spd, Glycine receptor strychnine-binding subunit, nmf11, Glra1, glycine receptor, alpha 1 subunit, oscillator, Glycine receptor 48 kDa subunit, ot, Glycine receptor subunit alpha-1 precursor, spasmodic

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:18.40 brain stem:127.10 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:141.90 retina:32.10 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.99 cerebellum:4 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.91 spine:8.84 retina:3.91 eye:3.99 artery/aorta:- vein:3.83 lymphnode:3.86 peripheral blood:- spleen:4.17 thymus:- bone marrow:3.91 adipose:3.77 bone:3.75 skin:3.67
CAGE cerebrum:0.92 cerebellum:- brain stem:4.94 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:6.10 retina:- eye:- artery/aorta:0 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq cerebrum:2.36 cerebellum:2.36 brain stem:2.36 corpus callosum/glia:2.36 pineal gland:2.36 peripheral nerve:2.36 spine:2.36 retina:2.36 eye:2.36 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.81 placenta:3.81 prostate:3.94 ovary:3.59 testis:3.89 heart:4.04 muscle:4.09 esophagus:- stomach:3.88 intestine:3.80 colon:- liver/hepato:3.95 lung:3.70 bladder:3.85 kidney:3.91 pituitary:3.89 thyroid/parathyroid:- adrenal gland:3.67 pancreas:4.48 breast:3.86 salivary:3.71
CAGE uterus:0 placenta:0.11 prostate:0 ovary:0 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:- pituitary:1.63 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_020492
Gene ID 14654
Unigene ID Mm.89320
Probe set ID 1422277_at  [Mouse430_2]
Ensembl ID ENSMUSG00000000263

Orthologous Gene

Human[2]  NM_000171, NM_001146040
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR006028  Gamma-aminobutyric acid A receptor
IPR008128  Glycine receptor alpha1
IPR006201  Neurotransmitter-gated ion-channel

Link to Pubmed  (Pubmed ID)

489953
1334371
1371219
1424806
3429842
4557539
7507926
7874121
7891186
7920629
7920630
8062927
8298642
8406478
8733750
9051263
9070927
9087981
9145798
9606417
9812897
10349636
11042159
11076688
11076861
11217851
11275284
11685575
11742725
11923415
12183685
12380014
12466851
12477932
12837931
12954867
16141072
16141073
16420443
16461637
16602821
16672662
16800867
16964444
17028313
17114051
17145751
17308032
17920294
18445051
18721822
19208226
19244519
19528249
20600650
20826655
21135047
21267068
21486794
21486797
21850450
22037201
22037202
22723691
22988142
22995908
23230213
23603522
23639821
24390226

Gene Ontology  (GO ID)

Biological Process

GO:0007340  acrosome reaction
GO:0007628  adult walking behavior
GO:0006820  anion transport
GO:0006821  chloride transport
GO:0034220  ion transmembrane transport
GO:0006811  ion transport
GO:0006936  muscle contraction
GO:0051970  negative regulation of transmission of nerve impulse
GO:0050905  neuromuscular process
GO:0050884  neuromuscular process controlling posture
GO:0007218  neuropeptide signaling pathway
GO:0051291  protein heterooligomerization
GO:0051260  protein homooligomerization
GO:0001508  regulation of action potential
GO:0060080  regulation of inhibitory postsynaptic membrane potential
GO:0042391  regulation of membrane potential
GO:0043576  regulation of respiratory gaseous exchange
GO:0002087  regulation of respiratory gaseous exchange by neurological system process
GO:0060013  righting reflex
GO:0001964  startle response
GO:0007268  synaptic transmission
GO:0060012  synaptic transmission, glycinergic
GO:0006810  transport
GO:0007601  visual perception

Cellular Component

GO:0030054  cell junction
GO:0034707  chloride channel complex
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0005622  intracellular
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0045202  synapse

Molecular Function

GO:0005254  chloride channel activity
GO:0005230  extracellular ligand-gated ion channel activity
GO:0016934  extracellular-glycine-gated chloride channel activity
GO:0016933  extracellular-glycine-gated ion channel activity
GO:0016594  glycine binding
GO:0030977  taurine binding
GO:0022824  transmitter-gated ion channel activity