glypican 3

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Synonym

OCI-5, Gpc3, glypican 3, Glypican-3 precursor

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:39.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:257.80

peripheral nerve:19.10

spine:-

retina:-

eye:76

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:425.80

skin:47.50

GeneChip

cerebrum:6.21

cerebellum:5.21

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.43

spine:6.24

retina:7.99

eye:7.10

artery/aorta:-

vein:13.07

lymphnode:6.20

peripheral blood:-

spleen:6.16

thymus:-

bone marrow:5.25

adipose:8.01

bone:6.03

skin:6.78

CAGE

cerebrum:1.60

cerebellum:-

brain stem:2.64

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.74

retina:-

eye:-

artery/aorta:4.61

vein:-

lymphnode:0.83

peripheral blood:-

spleen:1.73

thymus:1.95

bone marrow:-

adipose:-

bone:1.84

skin:4.10

RNA-seq

cerebrum:1.35

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:916.10

placenta:483.30

prostate:92.60

ovary:46

testis:44.30

heart:186

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:18.10

lung:50.20

bladder:-

kidney:177.30

pituitary:852.50

thyroid/parathyroid:-

adrenal gland:-

pancreas:150.10

breast:6.50

salivary:-

GeneChip

uterus:7.23

placenta:10.66

prostate:7.27

ovary:8.82

testis:5.98

heart:6.11

muscle:7.18

esophagus:-

stomach:7.32

intestine:6.31

colon:-

liver/hepato:5.86

lung:10.55

bladder:7.45

kidney:7.08

pituitary:8.50

thyroid/parathyroid:-

adrenal gland:9.25

pancreas:6.91

breast:8.40

salivary:6.30

CAGE

uterus:3.28

placenta:4.39

prostate:2.95

ovary:4.20

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:2.52

intestine:2.30

colon:2.10

liver/hepato:1.22

lung:5.35

bladder:3.96

kidney:-

pituitary:3.69

thyroid/parathyroid:-

adrenal gland:4.57

pancreas:3.21

breast:3.26

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.72

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0.89

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_016697
Gene ID	14734
Unigene ID	Mm.22515
Probe set ID	1450990_at [Mouse430_2]
Ensembl ID	ENSMUSG00000055653

Orthologous Gene

Human[4]	NM_001164617, NM_001164618, NM_001164619, NM_004484
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0009948	anterior/posterior axis specification
GO:0010171	body morphogenesis
GO:0030282	bone mineralization
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0060976	coronary vasculature development
GO:0035116	embryonic hindlimb morphogenesis
GO:0001822	kidney development
GO:0030324	lung development
GO:0008285	negative regulation of cell proliferation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0045926	negative regulation of growth
GO:0010466	negative regulation of peptidase activity
GO:0045879	negative regulation of smoothened signaling pathway
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0009887	organ morphogenesis
GO:0030316	osteoclast differentiation
GO:0030513	positive regulation of BMP signaling pathway
GO:0045807	positive regulation of endocytosis
GO:0046326	positive regulation of glucose import
GO:0045732	positive regulation of protein catabolic process
GO:0045880	positive regulation of smoothened signaling pathway
GO:0040008	regulation of growth

Cellular Component

GO:0031225	anchored to membrane
GO:0046658	anchored to plasma membrane
GO:0005576	extracellular region
GO:0005887	integral to plasma membrane
GO:0005764	lysosome
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0043395	heparan sulfate proteoglycan binding
GO:0030414	peptidase inhibitor activity
GO:0060422	peptidyl-dipeptidase inhibitor activity
GO:0005515	protein binding

glypican 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function